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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials
I Isabelle Thibault, MD, FRCPC

A Trial Evaluating Toxicity of SBRT and LDRB in Localized Prostate Cancer.

The goal of this clinical trial is to compare SBRT (Stereotactic Body RadioTherapy) to LDRB (Low-Dose Rate Brachytherapy with Iodine-125 seed implant) in patients with low and favourable intermediate-risk prostate cancer. The two main questions it aims to answer are : Does SBRT (Stereotactic Body RadioTherapy) for low and intermediate …

18 years of age Male Phase N/A
J Jacob Siddoway

Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study

The goal of this pilot study is to explore the efficacy of chloroquine in terminating persistent AF and assess its potential role as a pharmacological cardioversion agent for the management of AF.

18 years of age All Phase 2

Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project

The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms of high blood pressure during pregnancy, to guide treatment in the …

18 - 60 years of age All Phase 2
C Cristine H Jorge

Biofeedback Versus Vaginal Palpation to Teach a Voluntary Pelvic Floor Muscle Contraction

Pelvic floor muscle training (PFMT) is the first line treatment of urinary incontinence (UI), anal incontinence (AI) and mild/moderate pelvic organ prolapse (POP) in women. However, 25 to 40% of women with pelvic floor dysfunction symptoms are unable to voluntarily contract their pelvic floor muscle (PFM) and PFM proprioception of …

18 years of age Female Phase N/A
F Floris Bruinsma, MD

Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial

The purpose of this study is to assess the safety and efficiency of OAGB compared to RYGB

18 - 65 years of age All Phase N/A
C Christen Lauder

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

The purpose of this dose escalation study is to evaluate the safety profile of escalating doses and dose schedules of NXP900.

18 years of age All Phase 1
C Claudio Pollo, MD

Brain Circuitry Changes in Central Poststroke Pain: a Clinical and Neuroimaging Study

Central poststroke pain (CPP) is estimated to affect up to 10% of stroke patients and is one of the most difficult-to-treat conditions with a detrimental effect on patient's quality of life. So far, no drug has proven efficient to alleviate CPP and neuromodulation approaches including Deep Brain Stimulation (DBS) and …

18 - 75 years of age All Phase N/A
C Chien-Hung Chen, MD, PhD

A Study of PTX-9908 Injection for Non-resectable HCC With TACE

This is a multicenter, Phase I/II study in patients with non-resectable hepatocellular carcinoma following TACE treatment. Phase I (Open-label dose escalation) This study will be an open-label study with an Accelerated Phase and a Standard Phase. For the Accelerated Phase of the study, one patient per dose level (1 mg/kg, …

20 years of age All Phase 1/2
A Amy Kazaryan, MPhil

A Randomized, Placebo Controlled Trial of L Max in Healthy Adult Athletes

The goal of this study is to evaluate the lung-cleansing effects of L Max by measuring changes in Participant Reported Outcome (PRO) Scores and athletic performance. Researchers will compare the results of participants who take L Max and participants who take placebo (a look-alike substance that contains no active ingredient). …

18 - 60 years of age All Phase N/A
X Xiangdong Cheng

A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors

This study is an open, multicenter Phase I/II clinical trial, divided into two stages: dose exploration (including dose escalation and dose extension) and efficacy extension.

18 - 75 years of age All Phase 1/2

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