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SAPSo Paulo, Brazil Clinical Trials

A listing of SAPSo Paulo, Brazil clinical trials actively recruiting patients volunteers.

Found 303 clinical trials
J José Carlos Nicolau

Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes

Type 2 diabetes mellitus (T2DM) is one of the most important risk factors for atherosclerotic heart disease. Strategies focused solely on glycemic control have failed to demonstrate vascular events reduction in this population. On the other hand, new antidiabetic drugs recently have demonstrated significant decrease of cardiovascular mortality, raising the …

18 years of age All Phase 2/3

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens

The study proposes a planned, double-blind, non-inferiority clinical trial involving patients with febrile neutropenia and risk of extended-spectrum beta-lactamase (ESBL) infection. The goal is: Analyze the efficacy and tolerability of Ceftolozane/tazobactam (CEF/TAZ) compared to the current standard of care (meropenem) in patients with febrile neutropenia and risk of ESBL infection. …

18 years of age All Phase 4
T Tacianne Rolemberg Delamain, Medical doctor

Valvular Assessment of New Generation Aortic Replacement Devices

The VANGUARD study is an open-label, prospective, randomized trial comparing the long-term outcomes of two advanced bioprosthetic aortic valves, Dafodil® and INSPIRIS Resilia®, in patients undergoing aortic valve replacement (AVR). This study aims to provide robust data on valve durability, safety, and hemodynamic performance, particularly in younger patients who may …

18 - 65 years of age All Phase N/A
R Rodrigo Dominguez-Millan, Plastic Surgeon

Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction

The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction. The main questions this study seeks to answer are: Does CO2 lift reduce the extent of bruising at 7 days post-surgery? How …

18 - 65 years of age All Phase 4
A Amanda Vieira

Effect of Aromatherapy for Facial Aesthetics in Alleviating Signs of Aging: Pilot Study

Introduction: aesthetics is one of the specialties for professional nurses and presents a dialogue with Aromatherapy, a practice that uses essential oils (EO) from aromatic plants, being one of the most used integrative therapies for beauty care, youth and well-being. EOs are volatile compounds extracted from the most diverse parts …

45 - 55 years of age Female Phase N/A
C Celso RF Carvalho, PhD

Impact of Remote Vital Signs Monitoring in People Using Long-term Oxygen Therapy

Assess quality of life of patients using prolonged oxygen therapy

18 - 85 years of age All Phase N/A

The Solaris DE Endoprosthesis for the Treatment of AV Access Stenosis or Occlusion

The goal of this clinical trial is to demonstrate the safety and efficacy of Solaris DE Endoprosthesis in the treatment of stenosis or occlusion within the outflow circuit of the dialysis access including arteriovenous (AV) fistula and synthetic AV graft. Participants will be treated with Solaris DE Endoprosthesis. Researchers will …

18 years of age All Phase N/A
M Marcia Volpe, Doctor

Positive Pressure Therapy to Optimize LUNG Function After Heart Surgery

The most common cardiac surgeries are myocardial revascularization and valve replacement or plastic surgery. In the postoperative period of cardiac surgeries, the incidence of pulmonary complications ranges from 30% to 50% and is associated with increased length of hospital stay and morbidity and mortality. To reduce or minimize the occurrence …

18 years of age All Phase N/A
B Bruna E Catin Kupper, BSN, PhD

Study to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy

The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.

18 years of age All Phase N/A
F Fabiane L Freitas, BsC

One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG

The use of a graft from the left internal thoracic artery to the left anterior descending artery has become the gold standard for the indication of coronary artery bypass grafting. However, choosing a graft for the second-best coronary artery, focusing on long-term patency, is still a challenge. The saphenous vein …

18 - 75 years of age Female Phase N/A

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