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Kogarah, Australia Clinical Trials

A listing of Kogarah, Australia clinical trials actively recruiting patients volunteers.

Found 321 clinical trials

Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS

The goal of this project is to see if two new potential treatments (defactinib and the combination tablet of decitabine/cedazuridine) can safely be combined to improve outcomes in people with high-risk myelodysplastic syndrome (MDS), certain forms of Acute Myeloid Leukaemia (AML), and Chronic Myelomonocytic Leukaemia (CMML). Decitabine/cedazuridine is approved for …

18 years of age All Phase 1

Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction

The study's purpose is to understand the appearance of your prostate-specific membrane antigen (PSMA) PET scan after you take 14 days of treatment with a drug called dasatinib alone or in combination with anti-testosterone drug call darolutamide. Who is it for? You may be eligible to join this study if …

18 years of age Male Phase 2

Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer

To facilitate the clinical testing of seviteronel and dexamethasone (SEVI-D) in combination with docetaxel in androgen receptor (AR) positive triple-negative breast cancer.

18 years of age All Phase 1/2
K Kathleen Dorris, MD

MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

MEKTOVI (binimetinib) is an oral, highly selective reversible inhibitor of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2. The biological activity of binimetinib that has been evaluated bith in vitro and in vivo in a wide variety of tumor types In this Phase II, the drug will be used …

1 - 25 years of age All Phase 2

Study of Intratumoral IVX037 in Patients With Advanced or Metastatic Solid Tumours

This is a Phase 1 open-label, non-randomized, multi-center clinical trial of intratumoral IVX037 in people with micro satellite-stable (MSS) colorectal or gastroesophageal cancer metastatic to liver, or advanced ovarian cancer.

18 - 85 years of age All Phase 1

Bipolar Androgen Therapy + Carboplatin in mCRPC

The purpose of this study is to determine the efficacy of BAT and carboplatin in men with metastatic castrate-resistant prostate cancer (mCRPC).

18 years of age Male Phase 2
J James H McAuley, PhD

TITAN Trial: Reducing Phantom Limb Pain in People With Amputations

The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain. The main question it aims to answer is: In individuals who have undergone amputations and are experiencing phantom limb pain, what is the …

18 years of age All Phase N/A

Evaluation of NB1 Bone Graft Following Lumbar Interbody Arthrodesis

The objective of this clinical study is to evaluate the safety and effectiveness of NB1 Bone Graft in subjects with degenerative disc disease undergoing transforaminal lumbar interbody fusion. It is estimated that up to 30 participants will be enrolled in approximately 3 clinical sites. During baseline and follow-up assessments, patients …

17 - 70 years of age All Phase N/A
L Lynn Fukusima

A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

A double-blind, active-controlled, multiple-ascending dose, safety study of aerosolized RSP-1502 in subjects with cystic fibrosis Pseudomonas aeruginosa lung infection.

18 years of age All Phase 1/2
M Monica Osorio

Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma

The goal of this clinical trial is to test neoadjuvant dual immunotherapy in Merkel cell carcinoma with the aim to improve recurrence-free survival

18 years of age All Phase 2

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