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Brookvale, Australia Clinical Trials

A listing of Brookvale, Australia clinical trials actively recruiting patients volunteers.

Found 246 clinical trials
S Sue Cranmer

Working Out M0 Bipolar Androgen Therapy

The WOMBAT study will test if BAT can prolong the time it takes for nmCRPC prostate cancer to become detectable in other areas of the body (metastatic disease). Approximately 69 participants over the age of 18 with castrate resistant prostate cancer, no evidence of metastatic disease (M0) on conventional imaging …

18 years of age Male Phase 2

Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes

This study is designed to evaluate the safety and effectiveness of endoscopic intestinal re-cellularization therapy in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering medications.

22 - 70 years of age All Phase N/A
L Lisa Fuhrmeister

A Randomised Clinical Trial of a Digital Self-management Package for People With Interstitial Lung Disease

The goal of this clinical trial is to compare REBUILD-SM (a purpose-built smartphone app and self-management package) with standard care in people with interstitial lung disease (ILD). The main question it aims to answer is: • Does REBUILD-SM improve health-related quality of life, symptoms, anxiety, self-efficacy and physical activity for …

18 years of age All Phase N/A
U Uyen Le, BSN, RN

Positioning of Esketamine Treatment in the Real-world Management of Depression

The goal of this naturalistic, open label, single arm intervention study is to investigate the effects of Esketamine in treating depression.The main aims to answer are: to investigate whether Esketamine is effective when added to ongoing antidepressant treatment to identify patient characteristics that will determine a therapeutic response to Esketamine …

18 - 65 years of age All Phase 4
G Grigori Kaplan, PhD

A Dual Orexin Receptor Antagonist to Reduce Biomarkers of Neurodegeneration in Adults With Insomnia.

The goal of this clinical trial is to explore the potential neuroprotective benefits of a dual orexin receptor antagonist (DORA) in adults with insomnia. The main questions it aims to answer are: Does the DORA reduce blood-based phosphorylated TAU181, in adults with insomnia, when compared to placebo Does the DORA …

40 - 65 years of age All Phase 2
H Hannah Ellis

International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry

The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The …

18 years of age All Phase N/A
E Eugene DePasquale, MD

Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation

Demonstrate the impact of the Molecular Microscope Diagnostic System as the standard of care for heart transplant patients.

18 years of age All Phase N/A
B Beata Bajorek, BPharm DipHospPharm PhD

AusCADASIL: An Australian Cohort of CADASIL

The aim of this project is to establish an Australian cohort of patients diagnosed with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). This study will examine the clinical features and longitudinal course of CADASIL. Outcome measures include neuropsychological profile, neuroimaging, genetics, blood biomarkers, and retinal imaging.

18 years of age All Phase N/A
R Rinaldo Bellomo, Professor

The EXCEL Registry of Patients Requiring ECMO

ECMO is associated with significant costs, risks and requires specialist training and expertise. EXCEL is a novel, high-quality, detailed prospective registry of patients requiring ECMO in Australia and New Zealand. The registry provides information on patient selection, complications, costs and patient reported outcome measures. EXCEL uses the Theoretical Domains Framework …

18 years of age All Phase N/A
B Boston Scientific Clinical Research

Patient Retrospective Outcomes (PRO)

This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.

18 years of age All Phase N/A

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