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ulcers Clinical Trials

A listing of ulcers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 464 clinical trials
D Daniel O'Brien, A/Prof

Telacebec (T) Treatment in Adults With Buruli Ulcer (BU).

The goal of this interventional clinical trial is to determine if treatment with 4 weeks of telacebac (T) will completely heal lesions in participants with Buruli ulcer (BU) by 52 weeks after treatment initiation, without relapse and/or surgery. Males and females age 18 and older will be included. • Participants …

18 years of age All Phase 2
M Min Shi

Nicotinamide Riboside in Ulcerative Colitis

This is a randomized, double-blind pilot study of Nicotinamide Riboside (NR) in Pediatric-onset Ulcerative Colitis (UC).

- 18 years of age All Phase N/A
P Philip Voorneveld, MD, PhD

JAK Inhibition in Ulcerative Colitis

The treatment for Ulcerative Colitis (UC) aims to achieve and maintain remission and is usually lifelong and expensive. Current available medications are unable to break the cycle of chronic inflammation, and still a significant proportion of patients will fail to respond (primary non-response) or lose response over time (secondary non-response). …

16 - 65 years of age All Phase N/A
J Jenny Sauk, MD

Hyperbaric Oxygen Therapy for Ulcerative Colitis

Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue oxygenation. Two small prospective randomized controlled trials have demonstrated that the delivery of HBOT to UC patients hospitalized for acute moderate …

18 - 85 years of age All Phase N/A
R Reham Elshafiey, PhD

Nitazoxanide in Patients With Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel Disease (IBD) that primarily affects the rectum and colon. The severity and persistence of mucosal inflammation are associated with morbidity and mortality.

18 - 65 years of age All Phase 2
R Reham Elshafiey, PhD

Rupatadine in Patients With Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory condition that primarily targets the large intestine. Although substantial progress has been made in treatment modalities-especially with the development of immunomodulatory drugs and biologic therapies-managing UC continues to present significant challenges. At present, there is no definitive cure, and current treatment strategies are …

18 - 70 years of age All Phase 2

Alpha Lipoic Acid in Ulcerative Colitis

This study aims at evaluating the efficacy and safety of alpha-lipoic acid as adjuvant therapy to mesalamine in patients with mild to moderate ulcerative colitis due to its effect as anti-oxidant and anti-inflammatory drug which can help to improve disease.

18 years of age All Phase N/A
M Menofia university Hospitals

Desloratadine in Patients With Ulcerative Colitis

The purpose of this study is to investigate safety and therapeutic efficacy of antihistamine (desloratadine) on inflammation and disease activity when administered as adjuvant therapies with the traditional therapy 5-aminosalisylic acid (mesalamine) in patients with mild to moderate ulcerative colitis.

18 - 65 years of age All Phase 2
G Godwin Kpoton

Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy

Buruli ulcer (BU) is a skin Neglected Tropical Disease (NTD) that is caused by Mycobacterium ulcerans. It affects skin, soft tissues and bones causing long-term morbidity, stigma and disability. The greatest burden falls on children in sub-Saharan Africa. Treating BU requires 8-weeks with daily rifampicin and clarithromycin, wound care, and …

5 - 70 years of age All Phase 2

SUTURE-CLOSURE OMENTOPEXY VERSUS OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER

The present study will be conducted to assess whether there is a direct benefit associated with modified-Graham's omentopexy (MGO), above and beyond the benefit associated with Graham's omentopexy (GO) in the treatment of perforated duodenal ulcers. We attempted to answer the question whether primary closure of the perforation in MGO …

years of age All Phase N/A

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