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traumatic-brain-injury Clinical Trials

A listing of traumatic-brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 269 clinical trials
Z Zhanfeng Niu, Doctor

Wearable Device-Based Analysis of the Relationship Between Sleep Patterns and Clinical Prognosis in Patients With Traumatic Brain Injury

In patients with traumatic brain injury, post-traumatic sleep patterns have the potential to impact clinical prognosis. While some progress has been made in the study of sleep and prognosis in patients with traumatic brain injury, there is still lack of research on the relationship between sleep and clinical prognosis in …

18 - 60 years of age All Phase N/A
L Low Jaclyn

Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention

The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems. This is due to a lack of normative data for older adults and reliable risk stratification methods to develop effective approaches to the prevention of frailty. In this study, …

50 years of age All Phase N/A
W Wolmet Haksteen, MD

Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of Consciousness

Patients with acute severe brain injury are usually admitted to the Intensive Care Unit. A substantial proportion of these patients will have disorders of consciousness (DOC) after interruption of sedation. It is difficult to reliably predict neurological outcome in these patients. Dependent on the extent of permanently damaged brain areas, …

18 years of age All Phase N/A

Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury

The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between them in weaning outcome of traumatic brain injury patients undergoing invasive mechanical ventilation.

18 - 65 years of age All Phase N/A
N Nils Berginström, PhD

Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries

For the last decades, many aspects of human life have been altered by digital technology. For health care, this have opened a possibility for patients who have difficulties travelling a long distance to a hospital to meet with their health care providers over different digital platforms. With an increased digital …

18 years of age All Phase N/A
G Guoyi Gao, MD

Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury

The goal of this prospective, multicenter, observational, cohort trail is to explore the pattern of brain temperature-brain pressure association in acute brain injury and to clarify its predictive value for prognosis and neurological function 30 days after acute brain injury.

18 - 65 years of age All Phase N/A
P Paul Lee

Evaluation of an EEG Based Concussion System

This study will evaluate the accuracy of a new concussion system at detecting concussions. The investigators will be evaluating the degree to which data collected with the device agrees with a physician's determination of a concussion. The system captures an electroencephalograph (EEG) potential when a light is flashed into the …

9 years of age All Phase N/A
M Melanie Boltzmann, PhD

Prognostic Factors to Regain Consciousness

The study aims to identify factors that predict the medium and long-term outcome of patients with disorders of consciousness (DOC) undergoing early neurological rehabilitation. In this prospective, observational study, 130 DOC patients are going to be included (36 months). At study entry, different routine data, disease severity and functional status …

18 - 85 years of age All Phase N/A
C Caitlin Guzowski, MBA, MHA

Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation

This trial will evaluate the safety and efficacy of RIC HIDT transplant protocol following fludarabine and intermediate-dose TBI 800 cGy utilizing PBSC as the stem cell source.

18 years of age All Phase N/A

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