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Eye Disease Clinical Trials

A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 359 clinical trials
P Pamela Hoffman, MS

Corneal Elastography and Patient Specific Modeling

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and …

16 - 80 years of age All Phase N/A
F Francisco Blazquez Arauzo, MD, MsC

Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglandins

Glaucoma is a chronic optic neuropathy whose main modifiable risk factor is an abnormally elevated intraocular pressure. The aim of glaucoma treatment is to slow the progression of the disease by reducing intraocular pressure. Prostaglandin derivatives are the most effective topical drugs in reducing intraocular pressure (IOP). Among these, latanoprost …

18 - 99 years of age All Phase N/A
C Chinmay Deshpande, M.Optom.

Eye Pressure Lowering Surgery

The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.

18 - 85 years of age All Phase N/A
G Georgios Labiris, MD, PhD

Identification of Minimum Focal Points in Vision Curve Formation

The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the results to measurements acquired from participants that underwent uncomplicated pseudophakic presbyopia surgery.

40 - 80 years of age All Phase N/A
G Georgios Labiris, MD, PhD

Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistance

The primary objective of this study is to compare the postoperative visual acuity curves of patients that underwent one of the following surgical procedures: Insertion of an extended depth of focus intraocular lens with digital assistance and insertion of an extended depth of focus intraocular lens without digital assistance.

45 - 80 years of age All Phase N/A
W Wei-Lun Huang, MD

Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma

Background Intact corneal epithelium is important for the defense on the ocular surface, and the function of limbal stem cells is crucial to maintain its integrity. Certain chronic eye diseases, such as glaucoma, require long-term medication use. However, glaucoma patients often exhibit corneal punctate erosions and ocular surface inflammation. In …

18 years of age All Phase N/A
I Ingeborg Stalmans, Phd

Vitreopapillary Interface and Optic Disc Morphology

The vitreous fills the posterior chamber of the eye and is firmly attached, at the posterior pole, to the macula and the optic nerve head (ONH). With formation of a stepwise posterior vitreous detachment (PVD) exerted tractional forces could influence retinal functioning. Especially in patients with glaucoma the influence of …

18 years of age All Phase N/A
P Pukhraj P Rishi, MBBS

To Study the Effects of Refractive Surgery on OCT Measurements in the Eye

Corrective eye surgeries, such as Lasik, are widely used to correct focusing problems such as myopia, or nearsightedness. Often these patients develop other conditions like myopic maculopathy or glaucoma which require monitoring with optical coherence tomography (OCT). Since OCT is a light-based test and changes the refractive status of the …

19 years of age All Phase N/A
F Filippo Amore, MD

Quality of Life in Italian Visually Impaired Patients

Clinical register of visual rehabilitation activity and observational study on the validation of the VA LV VFQ questionnaire in the Italian context

18 years of age All Phase N/A
K Ksenya Tereshchenko

BEAM: Brain-Eye Amyloid Memory Study

The main objectives for this study are: To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative dementias against standard cognitive assessments and brain imaging measures; and To assess the potential utility of ocular assessments for early detection …

50 - 90 years of age All Phase N/A

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