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Opioid Use Disorder Clinical Trials

A listing of Opioid Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 182 clinical trials
P Paul A Nuzzo, M.A.

Cannabis and Opioid Use Disorder

This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes.

18 - 55 years of age All Phase 1
A Annabelle Belcher, PhD

Ketamine for Opioid Use Disorder

The goal of this clinical trial is to learn if ketamine works to reduce craving for opioids in adults entering methadone treatment for opioid use disorder. The main questions it aims to answer are: Does ketamine reduce craving for opioids in patients with opioid use disorder? Does ketamine reduce symptoms …

18 - 65 years of age All Phase 2
G Gregory Sahlem

OUD (Opioid Use Disorder) Target Trial

In this research study the investigators will work with 80-participants with opioid use disorder who are starting treatment with the medication buprenorphine and are trying to quit using opioids. The investigators are trying to learn two things: Can an MRI brain marker be used to predict which participants will be …

18 years of age All Phase N/A
M Megan Ivey, MS

Autobiographical Memory in Opioid Use Disorder

The research study is being conducted to better understand memory function in people with opioid use disorder (OUD) and whether memory training can improve the symptoms and lives of people with OUD. Further, this study seeks to identify how brain and heart activity contribute to memory function and OUD symptoms. …

18 - 60 years of age All Phase N/A
M Michael Bogenschutz, MD

Psilocybin for Opioid Use Disorder (OUD)

This is a double-blind, adaptive, 2-stage, multi-site, phase 2 randomized controlled clinical trial designed to evaluate effects of moderate and high dose psilocybin, relative to low-dose psilocybin control, in OUD patients who continue to use illicit opioids in spite of adherence to standard-of-care treatment with methadone. Up to 480 participations …

18 - 65 years of age All Phase 2
A Amber Jarnecke, PhD

Social Functioning in Opioid Use Disorder

Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treatment outcomes are poorly understood. This study will utilize both data from both patients with OUD and their concerned significant other (CSO) to examine associations between specific …

18 years of age All Phase N/A
R Research Coordinator

Ketamine Assisted Psychotherapy for Opioid Use Disorder

This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.

18 years of age All Phase 1/2

Neuroplasticity in Maternal Opioid Use Disorder (OUD)

Opioid use disorder (OUD) remains a major public health problem particularly for mothers in the perinatal period, for whom stress, relapse rates, and risk for overdose are elevated. The perinatal period is characterized by significant neural reorganization that determines outcomes for mothers and infants. OUD is also associated with neural …

21 - 45 years of age Female Phase N/A

LIFU for Treatment for Refractory Opioid Use Disorder

This is a randomized, double-blind, sham-controlled, partial crossover study investigating LIFU targeting the NAc and VC for participants with severe, treatment refractory OUD.

22 - 60 years of age All Phase N/A
A Ahmad Mahan

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

This study aims to understand how ibogaine treatment may change brain activity and symptoms in people with moderate-severe opioid use disorder (OUD), as defined by the DSM-5. Ibogaine is a plant-derived compound that some studies suggest can reduce opioid cravings and withdrawal. Participants in this study will already be independently …

21 - 65 years of age All Phase N/A

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