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Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 218 clinical trials
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

The Impact of Heavy Alcohol Use on Saliva and Oral Health

Background People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke. Researchers want to learn more about how to identify developing inflammation in the mouth. They also want to know …

18 - 100 years of age All Phase N/A
M Michael Smolka, Prof. Dr.

Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder

The first aim of this study is to establish the role of maladaptive reliance on habits for impaired control in addiction, employing a novel task - the Action-Sequence-Task (AST), which assesses interference between habitual and goal-directed control. The AST, along with the developed computational model, will be employed to test …

18 - 65 years of age All Phase N/A
C Catharine E Fairbairn, Ph.D.

Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study

In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.

21 - 30 years of age All Phase N/A
T Torgeir G Lid, MD PhD

Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems

Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway. The highest increase is found in older adults, in line with the development in most other countries in the western …

21 years of age All Phase N/A
M Maximilian Pilhatsch, Prof., MD, PhD

Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer

Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans. The investigators aimed to investigate the impact of acute and chronic stress on Pavlovian-to-instrumental transfer (PIT), how …

16 - 65 years of age All Phase N/A
M Maximilian Pilhatsch, Prof. Dr.

Role of Pavlovian Mechanisms for Control Over Substance Use

During the first funding period (1st FP), the investigators developed a novel full Pavlovian-to-instrumental transfer (PIT) task that allows assessing both, general and specific PIT to investigate whether specific PIT differs between alcohol use disorder (AUD) and control subjects. Preliminary analyses of the full transfer task indicate that AUD participants …

18 - 65 years of age All Phase N/A
J Jamie R Pogue, BA

Improving Remote Breathalyzer Procedures Used by Clinicians and Researchers to Remotely Monitor Alcohol Use

Remote breath alcohol monitors have been increasingly adopted for use in clinical, research and forensic settings to monitor alcohol use because they offer several key advantages over other available monitoring methods. However, it remains unknown if remote breathalyzers reliably detect alcohol use because there is up to a 10-hour window …

21 years of age All Phase N/A
V Vanessa Bloch, PU PH

Semantic Networks in Alcohol Use Disorder Patients: Exploratory Study

Alcohol Use Disorder (AUD) is a major public health problem, characterized by a high rate of relapse. Chronic and excessive alcohol consumption notably induces frontal brain alterations and cognitive impairments such as executive dysfunction and an attentional bias for alcohol, participating to the risk of relapse. In effect, AUD patients …

30 - 60 years of age All Phase N/A
A Alex Schmidt

Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery

The overarching goal of this study is to develop and examine the feasibility of a music-listening intervention that can be deployed in "real time" to regulate emotions and reduce momentary stress among young adults within the first 12 months of recovery from alcohol use disorder. We design the study with …

18 - 35 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)

Background Alcohol use disorder (AUD) is the most common substance use disorder in the world. Long-term AUD can affect a person s sense of taste and smell. This natural history study will compare alcohol drinking behaviors and measures of taste and smell in people with and without AUD. Objective To …

18 - 65 years of age All Phase N/A

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