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Dry Eye Disease Clinical Trials

A listing of Dry Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 85 clinical trials
P Patricia Lesho

2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD

Evaluate and study the immunologic changes to the ocular surface in cancer patients.

18 years of age All Phase N/A
R Ruobing Xia

Telemedicine Evaluation of Dry Eye Disease Using a Portable Automatic Ocular Surface Imaging Device (PAOSID)

This study aims to evaluate the diagnostic accuracy and grading consistency of a mobile phone-attached portable automatic ocular surface imaging device (PAOSID) for assessing dry eye disease (DED). Both patients diagnosed with DED and healthy volunteers will undergo conventional clinical imaging, including white-light anterior segment photography, corneal fluorescein staining (CFS) …

18 years of age All Phase N/A
D Daniela S Nosch, Bsc MSc PhD

Role of Corneal Nerves in Dry Eye Disease

This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.

18 years of age All Phase N/A
G Gerhard Garhöfer, MD

Assessment of TFT by OCT in Healthy Subjects and Subjects With DES

Dry eye syndrome (DES) is a highly prevalent ocular condition with potential severe consequences for affected patients. DES can be either caused by decreased tear production or increased tear evaporation, both leading to an instable tear film. Despite many efforts, generally accepted methodologies to diagnose, assess the severity and monitor …

18 years of age All Phase N/A
R Reda Zemaitiene

The Pattern of Dry Eye Disease After Cataract Surgery

This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.

50 - 90 years of age All Phase N/A

Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye

Primary Sjögren's syndrome is a chronic autoimmune disease that primarily involves exocrine glands, most commonly manifested in dry eye, dry mouth, and in other systems of the body.

18 - 80 years of age All Phase N/A
Y Yanru Shen

The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.

Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act …

20 - 35 years of age Female Phase N/A
M Mohamed Samir, Resident

Dryness Difference Between Before and After Phacoemulsification

The aim of this study is to compare tear film and tear film secretion before and after phacoemulsificaton cataract surgery

45 years of age All Phase N/A
C Chang Ching-Mao, M.D., Ph.D.

Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome

By analyzing the differential proteins in exosomes, this study aims to understand the pathological mechanisms of SJS and DES, identify potential diagnostic and therapeutic methods, and advance the diagnosis and treatment of these diseases.

20 - 75 years of age All Phase N/A
E Eric GABISON

Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye Syndrome (ALTESSE)

Modifications of cell surface markers (including EMMPRIN) were observed in conjunctival epithelial cells during dry eye syndrome ; this study aims to describe the modifications of the repartition of these cell surface markers before and after initiation of a treatment.

18 years of age All Phase N/A

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