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Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 85 clinical trials
M Mihai L Ciocirlan

Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver Failure

The investigators aim to study the predictive value of presepsin in ascites in newly admitted patients with chronic liver failure.

18 years of age All Phase N/A
E Emad Z Kamel, M.D.

Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome

Liver plays an important role in the metabolism of thyroid hormones, as it is the most important organ in the peripheral conversion of tetraiodothyronine (T4) to triiodothyronine (T3) by Type 1 deiodinase.

18 - 60 years of age All Phase N/A
Y Yu-Chen Fan

Single Cell Landscape of HBV-related Acute-on-chronic Liver Failure Patients

This study aimed to profile the peripheral blood immune cells of patients with HBV related acute-on-chronic liver failure using single-cell RNA sequencing to reveal the immunopathological mechanisms of HBV related acute-on-chronic liver failure.

18 years of age All Phase N/A
M Michael Praktiknjo, MD

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease

Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.

18 years of age All Phase N/A
A Adam J Milam, MD

Disparities Among Liver Transplant Patients

The purpose of this study is to inform healthcare interventions to reduce the disparities in liver transplant listing and in transplantation.

18 - 65 years of age All Phase N/A
L Liang Peng, Doctor

Long-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure

This study is to investigate the long-term outcomes and prognostic risk factors in patients recovered from hepatitis B virus related acute on-chronic liver failure.

18 - 65 years of age All Phase N/A
X Xian Zhong

Usability and Clinical Effectiveness of an Interpretable Deep Learning Framework for Post-Hepatectomy Liver Failure Prediction

The goal of this in-silico clinical trial is to learn about the usability and clinical effectiveness of an interpretable deep learning framework (VAE-MLP) using counterfactual explanations and layerwise relevance propagation for prediction of post-hepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC). The main questions it aims to answer …

years of age All Phase N/A
K Karen D Castro

Functional Assessment in Liver Transplantation

In order to ensure the equity of the liver allocation process, it is important to create objective, scientifically validated markers of frailty in patients with end-stage liver disease that accurately predict patient outcomes. Many measures have been developed to assess this clinical state in elderly patients, but none have been …

18 years of age All Phase N/A
J Jinjun Chen, PHD

SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury

In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the …

18 - 80 years of age All Phase N/A
D David Pereyra, MD, PhD

Vienna Hypothermic Oxygenated Machine Perfusion Study

In this observational cohort study data on all patients undergoing liver transplantation after hypothermic oxygenated machine perfusion at Medical University of Vienna will be prospectively recorded. Investigation of short- and long-term outcome in this cohort will be conducted.

18 years of age All Phase N/A

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