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Birth Defects Clinical Trials

A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 317 clinical trials
A Anna Bersano, MD

Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

The project aims to retrospectively and prospectively analyze a population of CADASIL patients in order to study the natural history of the disease by correlating the symptom spectrum with genetic risk and specific neuroradiological and biological markers Stratifying patients according to their disease risk, this could contribute to the discovery …

18 years of age All Phase N/A
A Alessandro Baj, Prof

Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis

Accuracy assessment through three-dimensional superposition of the post-operative volumetric CT and the digital therapeutic project files.

years of age All Phase N/A
J Jose A. Roshardt, Dr.

MRI-based 3D Hip Labrum and Cartilage Morphology in Patients With Hip Deformities Compared to Asymptomatic Volunteers

In this study, the investigators seek to describe the normal 3D hip joint morphology in asymptomatic volunteers and compare it to various hip joint deformities. Asymptomatic volunteers will be asked to undergo a non-contrast MRI of the hip at 3 Tesla, utilizing a high-resolution morphologic 3D sequence (3D T2 DESS) …

18 years of age All Phase N/A
G Gianluigi Pilu, MD

The Role of Ultrasonography in Pregnancy in the Study of Fetal Central Nervous System Malformations

The aim of this observational study is to evaluate the correlation between new ultrasound patterns and fetal central nervous system (CNS) malformations.

18 - 45 years of age Female Phase N/A
Z Zhiyong Shi, Doctor

Evaluation of Clinical Outcomes of Unruptured bAVMs Treated With Medical Management Alone Based on Multimodal CT

The purpose of this study is to investigate the role of multimodal CT in evaluating and predicting different clinical outcomes in patients with unruptured brain arteriovenous malformations with medical management alone. This study will be undertaken in the following aspects: Morphological, structural and imaging histological signal analysis based on multimodal …

3 - 80 years of age All Phase N/A
M Marina Cicerone, MD

Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children.

The severity of sleep disorders in patients with Chiari malformations can vary. The investigators propose to establish a correlation between the severity of sleep-disordered breathing (SDB) and the quantitative neuroradiological data of the airways, cranial base foramina, and posterior cranial fossae

3 - 18 years of age All Phase N/A
I Isil Taylan Cebi, M.D

The Evaluation of Piezo and Endonasal Osteotomy Methods on Postoperative Healing Process in Septorhinoplasty

The goal of this observational study is to compare the effect of Piezo and endonasal osteotomy techniques on the healing process of patients undergoing septorhinoplasty surgery. The main question[s] it aims to answer are: In which osteotomy technique the edema is lesser? Which osteotomy technique is better for thick vs …

18 - 65 years of age All Phase N/A
A Alessandra Familiari

Artificial Intelligence Algorithm for the Screening of Abnormal Fetal Brain Findings at First Trimester Ultrasound Scan

Visualization of the posterior fossa brain spaces, their spatial relationship and measurements can be obtained in the midsagittal view of fetal head, the same used for NT measurement (9), and plays an important role in the early diagnosis of neural tube defects, such as open spinal dysraphism (5), and posterior …

18 - 45 years of age Female Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

A Prospective Natural History Study of Lymphatic Anomalies

Background The lymphatic system is a network of vessels that carry a clear fluid called lymph through the body. Problems in the lymphatic system can cause pain, fluid buildup, and issues with immunity. There is much researchers do not understand about lymphatic anomalies. In this natural history study, they will …

1 - 100 years of age All Phase N/A

Scottish Advanced Fetal Research Study

In-utero exposure to drugs and chemicals through maternal smoking, alcohol use, drug abuse, prescription medicines and occupational/lifestyle exposures is widespread. Such exposures can alter fetal development and programming, leading to the effects becoming "locked in" from birth and causing long-term adverse consequences for the individual. These include costly and widespread …

16 years of age All Phase N/A

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