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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,170 clinical trials
L Lena Ellis

Post-Market Study to Assess iTind Safety in Comparison to UroLift

The study objective is to evaluate the safety of the iTind device comparied to UroLift.

50 years of age Male Phase N/A
G Gautier Müllhaupt, MD

Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in Medium to Large Size Prostates

Benign prostatic hyperplasia (BPH) is one of the most common diseases in men. As BPH progresses, surgical treatments often become necessary. Holmium enucleation of the prostate (HoLEP) is an established procedure in the surgical treatment of BPH, especially for medium to large prostates. The long learning curve, the length of …

45 years of age Male Phase N/A
M Mohamed F Salman, MD

Comparative Study Between Safety and Effectiveness of High Versus Low Power HOLEP

Holmium laser enucleation (HOLEP) has became a standard of treatment of large prostates that indicates surgery. HOLEP is widely used nowadays. Many settings are used but no optimal setting was world wide adopted. The aim of this trial is to assess the Low-power Holmium laser enucleation of the prostate (LP-HoLEP)and …

45 years of age Male Phase N/A
R Rabail Siddiqui, MPH, MHSc

Thulium Fiber Laser (TFL) vs Holmium MOSES for Treatment of Benign Prostatic Hyperplasia (BPH)

Benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate, places pressure on the urethra and causes urination and bladder problems. Transurethral Resection of the Prostate (TURP) remains the gold standard treatment in most centres for BPH. However, morbidity after TURP is high, especially bleeding requiring blood transfusion and late …

50 years of age Male Phase N/A
J Jill Moland

Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study

The goal of this clinical trial is to verify the continued safety and effectiveness for the Optilume BPH Catheter System.

50 years of age Male Phase N/A
P Pooja Talaty

Effects of TNF Blockade on Human BPH/LUTS

Specific Aim 1. To evaluate the efficacy of TNF antagonist action in BPH/LUTS Specific Aim 2. Define the consequences of TNF antagonist therapy on prostate tissue Specific Aim 3. Identify genetic predictors to stratify patients with differential response to TNF-antagonist therapy.

45 - 80 years of age Male Phase 2
M Mostafa M Mostafa, M.D., M.Sc. Urology, Ph.D. Uro

HoLEP vs BipolEP in Management of BPH Patients With Large Prostates

This is a non-inferiority prospective randomized comparative clinical trial aiming to prove the non-inferiority of bipolar enucleation of the prostate in comparison to holmium laser enucleation of the prostate in management of benign prostatic hyperplasia patients with large prostates and in turn its feasibility as an alternative procedure in hospitals …

50 years of age Male Phase N/A

A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms

The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the FloStent). All participants will undergo a flexible cystoscopy and those randomized to the treatment …

45 years of age Male Phase N/A
M Michael Baboudjian, MD

Local Anesthesia With Schelin Catheter in Rezum Treatment: a Randomized Controlled Trial

In a pilot study, water vapor therapy (RezumTM, Boston Scientific Corporation, Marlborough, MA) was proposed as a minimally invasive procedure for benign prostatic hyperplasia, but often requiring oral ± intravenous sedation or a transrectal prostatic block. Therefore, pain management during Rezum therapy remains a challenge and may lead to the …

18 - 80 years of age Male Phase N/A
R Rabail Siddiqui

Slim Sheath 22F Holmium Laser Enucleation of the Prostate (HoLEP) vs 26 F Sheath HoLEP for BPH: RCT

Holmium laser enucleation of the prostate (HoLEP) is routinely performed with 24F, 26F, and 28F laser scopes. Proponents of larger caliber scopes suggest that the larger scope size allows for improved visualization, hemostasis, and operative efficiencies. Proponents of a smaller scope diameter suggest that by eliminating the need for pre-HoLEP …

50 years of age Male Phase N/A

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