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Renal Failure Clinical Trials

A listing of Renal Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 606 clinical trials
F Francisca Saraiva, PhD

Algae Effects in Markers of Cardiovascular Risk and Gut Microbiome

The Western diet, rich in fat and sugar, contributes to cardiovascular risk and alters the body metabolism, specifically through the modulation of the microbiome. Microbiome is considered the "second genome", functioning as an endocrine-like organ. Gut microbiota-derived metabolites, namely trimethylamine- N-oxide and short-chain fatty acids have been associated with atherosclerosis, …

50 years of age All Phase N/A
A Ari Cisneros, Master

Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD

Patients whit chronic kidney disease (CKD) there is a high prevalence of nutritional disorders and negative changes in body composition, which is strongly associated with an increased risk of morbidity and mortality.

18 - 90 years of age All Phase N/A
L Lalantha Leelarathna, PhD FRCP

Automated Insulin Delivery in Adults With Advanced Kidney Disease

Diabetes is the leading cause of kidney failure in the UK. Many people with diabetes and advanced kidney failure inject themselves with insulin and do finger-prick blood glucose tests. Managing diabetes in people with advanced kidney disease is hard, with fluctuating glucose levels and an increased risk of unsafe low …

18 - 70 years of age All Phase N/A
U Ulf Bronas, PhD

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

The purpose of this study is to see if 6 months of home-based walking will improve memory, and brain structure and function, compared to health education in older adults that have chronic kidney disease and mild cognitive impairment.

55 years of age All Phase N/A
D Desmond Yap, MD

SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease

Lupus nephritis (LN) is a common manifestation in patients with systemic lupus erythematosus (SLE), and is an important cause of acute kidney injury and chronic kidney disease (CKD). Although the standard-of-care treatments for active severe LN are effective, a substantial proportion of LN patients still develop CKD and eventually end-stage …

18 years of age All Phase 2

Combination of Novel Therapies for CKD Comorbid Depression

The overall goal of the study is to determine if treatment of a Major Depressive Disorder (MDD) improves the outcomes of patients with chronic kidney disease (CKD). We showed that MDD is present in 25% of CKD patients and independently associated with progression to End-Stage Kidney Disease, hospitalization, and death. …

18 years of age All Phase 2

Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients

This study will investigate the impact of exercise on gastrointestinal function in peritoneal dialysis patients.

18 - 65 years of age All Phase N/A
M Michal L Melamed, MD

Bone in CKD Alkali Response (BICARb Pilot Trial)

The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease. The main questions it aims to answer are: To evaluate effects of potassium citrate treatment on bone quality and strength. To evaluate mechanism(s) underlying the effects of …

5 - 100 years of age All Phase 2/3
A Akilah King, MSW

Interactive Computer-adaptive Chronic Kidney Disease Education Program

The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD). The main question it aims to answer are: does computerized adaptive education (CAE) increase patients' knowledge about CKD self-care and renal replacement therapy (RRT) …

18 - 70 years of age All Phase N/A
M Menno Pruijm, Dr

Nephrospec Switzerland

This is a randomized, double-blind sham-controlled monocentric trial. 30 patients that are diagnosed with hypertension and with moderate to severe chronic kidney disease are included in this trial. 20 of them are randomized into the active treatment arm, 10 into the sham arm. Low-intensity extracorporal shock wave (Li-ESWT) sessions (arm1) …

18 - 80 years of age All Phase N/A

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