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Sleep Apnea Syndromes Clinical Trials

A listing of Sleep Apnea Syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 320 clinical trials
J Jiří Hynčica

This Research Project Studies the Relationship Between OSA and Nocturia.

The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.

18 years of age All Phase N/A
J Joshua Bock, PhD

A Study of Sex Differences in Neurocirculatory Control

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

20 - 70 years of age All Phase N/A
E Elisa Perger, MD

Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness

In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.

18 years of age All Phase N/A
P Phillip LoSavio, MD, MS

Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation

The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team will also determine if the treatment of Obstructive sleep apnea (OSA) by (hypoglossal nerve stimulation) HGNS will alter predictors of cardiovascular outcomes.

18 years of age All Phase N/A
M Miguel D Gallego, Medicine

Impact of Sleep Disorders on Innate Immunity in COVID-19 Patients

Sleep is an important modulator of the immune response, whereby sleep disturbances (ie, poor sleep quality, insufficient sleep and/or primary sleep disorder, obstructive sleep apnea (OSA)) contribute to inflammatory disease risk and dysregulation of immune response in front of infectious agents. The objective of this study is to evaluate the …

18 - 70 years of age All Phase N/A
A Allan I Pack, MBChB

Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype

The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symptom subtype.

18 - 75 years of age All Phase N/A
Y Yingqian Zhou

Unveiling the Neural Mechanisms of 5-HT7 in Sleep Apnea Induced by Arousal Dysregulation

Obstructive sleep apnea (OSA), recognized as a highly prevalent sleep breathing disorder with severe complications, features a complex etiology. Poor understanding of disease pathogenesis limits the overall efficacy of interventions. Studies have found that upregulation of 5-HT7 expression in the lateral hypothalamus (LH) could reduce arousal threshold (ArTH) and induce …

20 - 60 years of age All Phase N/A
B Bryan Humphrey

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

The purpose of this observational clinical study is to provide evaluation of long-term safety and effectiveness in a newly expanded patient population including patients with a higher AHI and a higher BMI.

18 years of age All Phase N/A
V Valentina Poletti

Brain Fog in Sleep Apnea

Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients. It compares two groups: those on CPAP treatment for at least 3 months and those not yet treated. Procedures: Severe OSA patients (AHI > 30) …

18 years of age All Phase N/A
C Chun-Hsien Tseng

TipTraQ Home Sleep Test Validation Study, VGH

A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional sleep test, known as polysomnography (PSG), conducted in a sleep center. The performance of the …

20 years of age All Phase N/A

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