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Kronisk bronkitis (KOL)/ Rygerlunger Clinical Trials

A listing of Kronisk bronkitis (KOL)/ Rygerlunger medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 103 clinical trials

Preserving Geriatric Muscle With an Osteoporosis Medication

Our goal is to demonstrate efficacy of the novel agent Denosumab to improve or preserve muscle health, strength, mobility and function in frail older adults.

65 - 100 years of age Both Phase 4
B Bari M Guzikowski, BA

Romosozumab Use to Build Skeletal Integrity

The purpose of this study is to find out if one year of romosozumab (Evenity®), a monthly injection given in the arm under the skin, prior to an infusion of zoledronic acid Reclast®, works to treat bone loss and prevent it from worsening in older women (ages 65 and older) …

65 - 100 years of age Female Phase 4

RECONFIRM - Study of AGN1 LOEP in Patients With Osteoporosis

The research will be conducted as a prospective, post-market, multi-center study within Europe. The maximum number of subjects to be treated is 150 across up to 20 sites. This will be a non-randomized and open-label study. The study will collect procedural, short- and long-term data on the safety and clinical …

- 100 years of age Female Phase N/A

Strength Training for Osteoporosis Prevention During Early Menopause

The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females. The main question it aims to answer are: -Is a 9-month resistance training intervention feasible (e.g., recruitment rates, protocol adherence, attrition) Secondary aims include examining …

45 - 60 years of age Female Phase N/A
W William Friedman

Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab Alone

This randomized open label clinical trial will evaluate the effect of continued denosumab alone over 18 months versus denosumab with added abaloparatide for 18 months. 70 postmenopausal women will be enrolled over a period of 18 months. The co-primary outcomes will be group differences in bone mineral density (BMD) of …

45 - 100 years of age Female Phase 4

Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis

Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality. Given potential side effects, hormone replacement therapy is no longer recommended for menopausal women with risk of becoming osteoporotic. The very significant decrease in the …

50 - 65 years of age Female Phase N/A

MAGnesium Effect With ANtiosteoporotic Drugs

Randomized pilot clinical trial to demonstrate superiority of bisphosphonate-magnesium combination over bisphosphonates alone in postmenopausal osteoporosis in slowing bone remodeling as assessed by C-terminal telopeptide of bone collagen type 1 (CTX) dosage.

50 - 100 years of age Female Phase 2
Y Yukio Nakamura, MD, PhD

Changes of Bone Turnover Markers and Bone Mineral Density After Osteoporosis Treatment

To examine the changes of bone mineral density and bone turnover markers after Bonviva treatment in osteoporotic patients

20 - 100 years of age Both Phase 4
Y Yukio Nakamura, MD, PhD

The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis

In the patients with osteoporosis, bisphosphonates (BPs) are a golden standard treatment. However, the bone turnover markers or the bone mineral density (BMD) are not improved in some osteoporotic patients even though they have taken BPs and alfacalcidol more than several years. In those case, the investigators better off prescribing …

- 100 years of age Both Phase 1
Y Yukio Nakamura, MD, PhD

Examination of Efficacy and Safety of Other Anti-Resorption Drugs After 2-year-Denosumab Therapy in Japanese Osteoporosis Patients

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in Japanese osteoporosis patients after 2-year-denosumab therapy: SERM and eldecalcitol treatment for 24 months Bisphosphonates and eldecalcitol treatment for 24 months Eldecalcitol treatment for 24 months

20 - 120 years of age Both Phase 2

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