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Chronic Obstructive Lung Disease Clinical Trials

A listing of Chronic Obstructive Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 495 clinical trials
M Mingming Deng, Doctor

Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: Can human lung stem cell proliferate in vitro. Can a lung organoid derived from patients with …

18 - 55 years of age All Phase N/A
P Phoebe H Lloyd-Evans

Developing Personalised Relative Physical Activity Thresholds in COPD.

The aim of this observational study is to translate the principle of individualised exercise prescription into the evaluation of daily absolute and relative intensity physical activity. The main questions this study aims to answer are: Phase 1: What does physical activity (intensity) mean to people with COPD? Phase 2: Are …

40 years of age All Phase N/A
C Chathurangi Pathiravasan, PhD

Effectiveness of the WearME System for COPD Severity and Respiratory Function

This observational study evaluates the effectiveness of the WearME system in monitoring COPD severity and respiratory function by comparing its measurements to standard spirometry, capnography, and other clinical assessments in 128 COPD participants.

21 - 100 years of age All Phase N/A
D David SC Hui, MD

A Study on COPD Phenotypes, Endotypes and Treatable Traits

Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and multisystemic disease with progressive increasing morbidity and mortality. COPD is now widely accepted as a heterogeneous condition with multiple phenotypes and endotypes.The recognition of COPD phenotypes and endotypes has significantly impacted the management of the disease. Furthermore, treatable traits (TTs) are …

40 years of age All Phase N/A
K Ke-Yun Chao, PhD

Association Between Cardiopulmonary Function and Plantar Pressure in Patients With Chronic Obstructive Pulmonary Disease

It aims to understand the differences in everyday mobility and activity capabilities among patients with varying disease progression and severity, to serve as reference indicators for evaluating the effectiveness of pulmonary rehabilitation exercise training.

45 - 65 years of age All Phase N/A
J Jean Louis Pépin, MD, PhD

Cardiovascular Risk and Chronic Obstructive Pulmonary Disease

The principal objective of the study is to measure parameters of inflammation, oxidative stress, and vascular, respiratory, and peripheral muscle function parameters, and identify parameters indicative of evolving cardiovascular risk (CVR) in COPD patients, using multivariate analysis.

18 - 85 years of age All Phase N/A
P Peter Ireland, MBBS

Eosinopenia in Severe COPD Exacerbation

The goals of this observational study are to identify factors independently associated with admission eosinopenia in patients with a severe exacerbation of chronic obstructive pulmonary disease (COPD) and to determine when blood eosinophil count (BEC) will recover to baseline stable state in patients who are admitted to hospital with a …

35 years of age All Phase N/A
M Mingming Deng, Doctor

Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector

The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector. Participants will use the self-developed pulmonary lobar ventilation detector …

18 - 90 years of age All Phase N/A
J Jean-Claude Pairon, Pr

Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD

COPD and non-COPD patients will be included in the study after collection of their non-objection. The exhalation will be collected to study the microbiological diversity of human exhalations. a second collection for the year +1 will be made, at the same time (between October and March).

18 - 70 years of age All Phase N/A
C Chris Landon, MD

CareCOPD - COPD Home Monitoring Study

This is a pilot study to demonstrate early validation of objective home-monitoring of Chronic obstructive pulmonary disease (COPD) patients by combining accurate and relevant patient data of medication and lung function (lung impedance) through patient-facing devices.

40 - 100 years of age All Phase N/A

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