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Celiac Disease Clinical Trials

A listing of Celiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,241 clinical trials

A SAD Study of HM17321 in Healthy Adult Participants

This is a Phase 1 study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of HM17321 after single ascending doses in healthy adult participants.

18 - 65 years of age All Phase 1
Y Yishan Huang, Ph.D

Bariatric Surgery Combined With GLP-1 Receptor Agonists Study

Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with single therapies. While bariatric surgery remains the most effective weight-loss intervention, postoperative weight regain and metabolic deterioration require attention. GLP-1 RAs offer distinct advantages for weight and metabolic improvement, and their combined application with surgery may …

18 - 60 years of age All Phase 1/2
R René VALERO, MD

Vitamin D and Its Metabolites Quantification in Adipose Tissues of Obese and Non-obese Patients.

Vitamin D (VD) is a pleiotropic hormone, involved in many physiological processes including calcium and phosphorus absorption. The VD metabolism begin to be well-known and involves a hepatic hydroxylation (mediated by enzymes, which belong to the cytochrome P450 family) leading to the production of the 25(OH)D, which corresponds to the …

18 - 65 years of age All Phase N/A
M Marta Ramon Krauel, MD PhD

Effects of the Postbiotic Blend ABB C3 on Adiposity and Glucose Metabolism in Children and Adolescents

This study investigates the effects of a postbiotic combination called ABB C3 on reducing body fat and improving metabolic health in children and teenagers. The study consists of a 3-month trial with half participants taking ABB C3 and the other half a placebo, monitoring body composition and blood markers. Afterward, …

8 - 18 years of age All Phase N/A
S Suzy Laroche

Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery

Sleeve gastrectomy (SG) has become the most commonly performed weight loss surgery, accounting for 60% of all bariatric operations worldwide. While technically easier with less side-effects and nutritional risks than other operations, SG is also associated with a higher risk of failure (20 to 40%). In such case, the most …

18 - 60 years of age All Phase N/A
E Eduardo Grecco

Endoscopic Treatment of Overweight and Mild Obesity with ORBERA365

INTRODUCTION: Obesity is a critical health condition associated with high rates of morbidity and mortality. Conservative therapies such as dietary restriction, physical exercise, and pharmacological treatments have not prevented the rising incidence of obesity. Bariatric surgery, while effective, is limited to a relatively small proportion of the global obese population …

18 years of age All Phase N/A
S Suzy Laroche

Single Anastomosis Versus Standard Duodenal Switch

Bilio-Pancreatic diversion with Duodenal Switch (BPD-DS) is the most effective bariatric procedure in terms of long-term weight loss and remission rate of Type 2 Diabetes. However, its technical difficulty and increased risk of long-term nutritional deficiencies have been a major hindrance to its diffusion. Recently, a " simplified " technique …

18 - 60 years of age All Phase N/A

Study of Safety and Efficacy of a Probiotic and Postbiotic in Overweight Individuals

Investigate the effect of a probiotic (live bacteria) and postbiotic (heat-treated bacteria) strains in overweight individuals.

19 - 75 years of age All Phase N/A
C Christopher Blesso, Ph.D.

Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.

18 - 70 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

Background At least 30% of Americans have fatty liver disease. This means that they store too much fat in the liver. At the moment lifestyle changes are the only way to treat this problem. Objective To test how (1) a low-carbohydrate diet and (2) a supplement called nicotinamide riboside (NR) …

18 - 65 years of age All Phase N/A

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