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Bowel Dysfunction Clinical Trials

A listing of Bowel Dysfunction medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 410 clinical trials
G Gordon Moran Professor

NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study

The goal of this observational study is to learn about the comparisons of inflammatory markers between IBD and non-IBD (control) participants. The main question it aims to answer is: Are there differences in inflammatory markers between IBD and non-IBD (control) participants.

16 years of age All Phase N/A
H Hao Zhang

Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression

Inflammatory Bowel Disease (IBD), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), significantly impairs patients' quality of life. Current monitoring of disease activity primarily relies on endoscopy combined with histological examination, which is associated with high costs, invasiveness, poor patient tolerance, and risks of complications. Additionally, disease activity indices and …

18 - 65 years of age All Phase N/A
N Naz Mohammed Salih, Dr.

Improved and Simplified Staining Technique for Dysplasia Detection in Colitis

Comparing chromoendoscopy to a digital staining technique and White light in patients with IBD attending scheduled surveillance colonoscopy

18 years of age All Phase N/A
M Maria Hermanson, PhD

Delayed Surgery in Inflammatory Bowel Disease

The timing of elective surgery in inflammatory bowel disease (IBD) may be crucial according to progression of the disease. In most cases, medical treatment has failed when surgery is discussed. If treatment with surgery then is delayed, complications may arise, such as fistula, severe inflammation with risk of perforation or …

18 years of age All Phase N/A
E Etienne Merlin

Host-microbiota-environment Interactions

Two types of inflammatory and autoimmune diseases (excluding monogenic diseases) can be distinguished in children: those similar to adult diseases but with an early onset (type 1 diabetes, inflammatory diseases of the gastrointestinal tract, rheumatoid arthritis with anti-CCP antibodies) and those specific to children that are not described in adults …

- 10 years of age All Phase N/A

The Effect of IBD Flares on Serum PSA

This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD …

40 - 69 years of age Male Phase N/A
C Cindy Canivet, CRA

Chronic Intestinal Pathologies Analytical Cohort at TouLouse

In the general population, the percentage of people with at least one digestive disease is 16.7%. Among these digestive diseases, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and patients who should benefit from digestive examinations as part of a screening oriented either by the patient's family history or following …

18 - 99 years of age All Phase N/A
M Matteo Rinaldi, MD

Comparison Diagnostic Tests for the Diagnosis of CYTOmegalovirus Organ Disease in Patients With intestinalBOweL Diseases

Observational, single-center, non-pharmacological, prospective study of adult patients affected by Inflammatory Bowel Disease (IBD) with an ongoing disease exacerbation requiring hospitalization

18 years of age All Phase N/A
A Antonio Giordano, MD, MSc, PhD

Body Composition Assessment and Monitoring in Inflammatory Bowel Disease

This is a single-center, prospective observational study aiming to describe changes in body composition (specifically, percentage of lean mass and phase angle) in patients with active inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The study will recruit patients with a confirmed IBD diagnosis who are starting biologic …

18 - 64 years of age All Phase N/A
E Emily W Lopes, MD, MPH

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow unaffected first-degree relatives (who do not have IBD) over time to understand if their behaviors, diet, and biomarkers for IBD can help predict …

14 years of age All Phase N/A

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