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Bowel Dysfunction Clinical Trials

A listing of Bowel Dysfunction medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 412 clinical trials
I Ida Hilmi

Dietary Modification In Inflammatory Bowel Disease Patients

This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED). The study will be conducted in inflammatory bowel disease patients in University Malaya Medical Centre, which are ulcerative colitis and Crohn's disease patients. The …

18 - 50 years of age All Phase N/A
A Abigail Basson, RD, PhD

Effect of Grapes in Inflammatory Bowel Disease

The overall objective of this pilot intervention study is to determine the impact of grape powder (46g/day freeze dried whole grape powder provided by the California Table Grape Commission) on the gut microbiotacomposition in adult patients with the IBD subtype Crohn's disease (CD).

18 - 65 years of age All Phase N/A
C Cagla Eskicioglu, MD

Postoperative Extended Venous Thromboprophylaxis in Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a relatively common disease that effects all age groups and carries significant morbidity and mortality. The initial treatment typically involves both short and long term medication, however when this is not enough to adequately control the disease, surgery is often required. The high morbidity and …

18 years of age All Phase N/A
C Charlotte Knatten Consultant, MD, phd

Infliximab Infusion Rates in Pediatric Inflammatory Bowel Disease

OBJECTIVES OF THE STUDY Investigate whether there are just as few infusion reactions with infliximab infusions of 60 min and 30 min. Investigate patient and nurse satisfaction with infusions of 60 min and 30 min. Investigate resource use in terms of total length of stay and use of nursing resources.

1 - 18 years of age All Phase N/A
R Robert Hoey, PhD

Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury

Bowel issues occur in nearly all people after spinal cord injury (SCI) and one major complication is fecal incontinence (accidents). This complication has been repeatedly highlighted by people living with SCI as particularly life-limiting and in need of more options for interventions. This study will test the effect of genital …

18 years of age All Phase N/A
F Faming Zhang, MD, PhD

Standardized Fecal Microbiota Transplantation for Ulcerative Colitis

The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body's metabolism. Evidence from animal and human studies strongly supports the link between intestinal bacteria and inflammatory bowel diseases (IBD). Dozens of studies reported its efficacy in treatment of severe Clostridium …

6 - 80 years of age All Phase 2/3

Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease

Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory bowel diseases (IBD). Adalimumab is a human monoclonal antibody against TNF-alpha, a pro-inflammatory cytokine that mediates the inflammatory response in IBD upon binding to the TNF receptors. Primary non-response to adalimumab is high in both CD and UC. Currently, there …

18 years of age All Phase 1/2
W Wouter B. Nagengast, Prof.

Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease

Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory bowel diseases (IBD). Risankizumab is a human monoclonal antibody against IL23 p19, part of a pro-inflammatory cytokine that mediates the inflammatory response in IBD upon binding to its receptor. Primary non-response to risankizumab is high in both CD and UC. …

18 years of age All Phase 1/2

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease. The investigators will be collecting some additional bloodwork and questionnaires at the time of participants infusions.

5 - 25 years of age All Phase 2
z zahra Sadek, PhD

Effect of Probiotic Administration on Patients With Inflammatory Bowel Disease

The study is a single-center, randomized, single-blinded, controlled trial conducted at ZHUMC's endoscopy unit. It aims to assess the short-term effects of probiotic administration on disease course, quality of life, and nutritional status among patients diagnosed with inflammatory bowel disease (IBD), specifically ulcerative colitis (UC) and Crohn's disease (CD). Patients …

18 - 65 years of age All Phase N/A

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