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Gastroesophageal Reflux Disease Clinical Trials

A listing of Gastroesophageal Reflux Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 79 clinical trials
M Michael J Rosen, MD

Mesh Vs Pledgets for Repair of Paraesophageal Hernia

The goal of this clinical trial is to compare whether the use of Ovitex mesh provides superior reduction in 2-year recurrence compared to pledgeted suture closure (no mesh) for patients undergoing paraesophageal hernia repair at the Cleveland Clinic. The main questions it aims to answer are: Determine whether there is …

18 years of age All Phase N/A

Effectiveness of Visceral Manual Therapy in Bruxist Patients With Gastroesophageal Reflux

Objective: check the effectiveness of visceral manual therapy on bruxist patients with gastroesophageal reflux. Design: Experimental, analytical, longitudinal, prospective, randomized, single-blind study with a blinded evaluator. Subjects: 68 subjects over 18 years old, with bruxism (diagnoses by a dentist) and gastroesophageal reflux (evidenced by the GERDQ test). Methods: Subjects will …

18 years of age All Phase N/A
G Gitte Zachariassen, MD, PhD

Treatment of Gastroesophageal Reflux Disease in Infants

Gastroesophageal reflux disease in infants is not fully understood. Infants are prescribed medical treatments that may not be effective or that contribute to adverse side effects and lead to concerns and expenses for the parents and healthcare system. Current guidelines recommend cow-milk-protein free diet as a first-line treatment, but these …

1 - 1 years of age All Phase 4
A Andree H Koop, MD

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.

18 years of age All Phase N/A

Famotidine and Antacids for Treatment of Dyspepsia

The aim of this study is to compare intravenous famotidine, an H2 receptor antagonist, and Maalox/ Mylanta, an oral antacid, in treatment of dyspepsia in the emergency department. The goal of this study is to reduce patients' pain based on the verbal numerical pain scale. The anticipated outcome is for …

18 years of age All Phase 4
J Jan Martínek, MD. PhD.

The Effect of Physiotherapy on Post POEM Reflux

Per-oral endoscopic myotomy has been used as a treatment method of esophageal achalasia. Patients who undergo POEM as a treatment of achalasia are often presented with development of reflux as a side effect of the surgery. Patients are then in need to use proton pump inhibitor drugs as a long …

18 - 60 years of age All Phase N/A

The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients

A prospective, open label, study designed to assess the affect of the Reflux Band® UES Assist Device (Reflux Band) on reflux in patients that have undergone lung transplantation.

18 - 80 years of age All Phase N/A
V Vasily Kropochev

Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence

This study is aimed to investigate the role of long-term diet adherence on manifestations of gastroesophageal reflux disease

18 - 80 years of age All Phase N/A
G Gokulakrishnan Balasubramanian, MD

Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:

Background \& Significance Chronic benign esophageal disorders such as Gastroesophageal reflux disease (GERD) and eosinophilic esophagitis are common gastrointestinal disorders affecting nearly 20% and 0.1% of the population, respectively. Although these conditions are frequent, the diagnosis of GERD or EoE requires complex decision making involving endoscopic examination, histopathological examination, and …

18 years of age All Phase N/A
K Koy Min Chue, MBBS, FRCSEd

Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction

Background Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE). The investigators' preliminary study suggests that the incidence of postoperative GERD and EE appears to be correlated with the preoperative presence of a lax …

21 - 65 years of age All Phase N/A

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