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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 326 clinical trials
G Georg Dorfmuller

EPC Performance Investigation for StereoElectroEncephaloGraphy

The objective of this multicentre study is to collect preoperative, intra operative, early, short, intermediate and mid-term(one years) on the related clinical complications and functional outcomes of market-approved Alcis products to demonstrate safety and performance of these devices in a real-world setting.

18 - 65 years of age All Phase N/A
F Fabrice Bartolomei

Multi-scale Analysis of Physiological Brain Networks

The SEEG implantation is performed on purely clinical criteria for preoperative diagnosis. Magnetoencephalography and EEG are purely passive techniques that do not involve any additional risk. This project is a continuation of an existing project in which it was demonstrated the feasibility of simultaneous SEEG and MEG/EEG recordings.

12 years of age All Phase N/A

A Survey of Midazolam in People With Status Epilepticus

This study is a survey in Japan of midazolam oromucosal solution used to treat people with status epilepticus. The study sponsor will not be involved in how the participants are treated but will provide instructions on how the clinics will record what happens during the study. The main aim of …

years of age All Phase N/A

A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning - Nelli

Nelli is a video-based non-EEG physiological seizure monitoring system. This study is a blinded comparison of Nelli's identified events to gold-standard video EEG review in at-rest pediatric subjects with suspected motor seizures.

6 - 21 years of age All Phase N/A
K Krzysztof A Bujarski, MD

Effects of Social Feedback on Intracranial EEG

This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked …

18 - 65 years of age All Phase N/A
L LAure PETER-DEREX, Dr

Sleep and Rehearsal-Driven Memory in Epilepsy

Memory consolidation transforms unstable memory traces into lasting representations, a process enhanced by both sleep and rehearsal during learning. Rehearsal is thought to accelerate consolidation by inducing memory reactivations that resemble those occurring during sleep. However, the respective mechanisms of sleep- and rehearsal-induced consolidation-and their potential interactions-remain poorly understood, especially …

18 - 65 years of age All Phase N/A
C Chun-Hong Shen

Idiopathic Generalized Epilepsy Syndromes

The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of …

4 - 40 years of age All Phase N/A
M Marina Azevedo, BSc

A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning (USF)

Increased computational power has made it possible to implement complex image recognition tasks and machine learning to be implemented in every day usage. The computer vision and machine learning based solution used in this project (Nelli) is an automatic seizure detection and reporting method that has a CE mark for …

18 - 99 years of age All Phase N/A
M Marco De Curtis, MD

Study for the Diagnosis and Treatment of Drug-resistant Focal Epilepsies

Epilepsy is a clinical condition that affects about fifty million people worldwide, with an estimated occurrence of 16-51 new cases per 100,000 people each year. In 60% of these patients, the origin of seizures is due to a localized (focal) alteration of the brain. In about 25 percent of patients …

18 years of age All Phase N/A

PET/MRI/EEG Imaging Study in Epilepsy

This study aims to better understand how epilepsy alters brain function through neuroimaging of healthy people and people with epilepsy. The study investigates how changes in brain metabolism (sugar consumption, measured by positron emission tomography [FDG-PET], and blood flow, measured by functional magnetic resonance imaging [fMRI]) relate to abnormal interictal …

18 years of age All Phase N/A

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