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Heart Valve Disease Clinical Trials

A listing of Heart Valve Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 315 clinical trials

Screening of Valvular Heart Disease Using Single-channel Electrocardiogram

It is a prospective, controlled, single-center, observational, non-randomized study. The study is planned to include at least 1000 patients over 18 years old in the training sample and 200 patients over 18 years old in the test sample (the total number of patients is at least 1200 people). All patients …

18 years of age All Phase N/A
X Xiaodong Zhuang, Dr

Detection of Valvular Heart Disease Using Artificial Intelligence-based Stethoscope

The aim of this study is to develop a deep learning-based application of heart sounds in the diagnosis of valvular heart disease, which can be used to screen patients with valvular heart disease and promote earlier clinical monitoring and intervention.

18 - 100 years of age All Phase N/A
X Xiaodong Zhuang, Dr

Mechanism and Effect of Novel Metabolites on Valvular Heart Disease

Valvular heart disease (VHD) is a leading cause of loss of physical function, reduced quality of life and increased longevity.The epidemiology of VHD varies widely across the globe, with functional and degenerative diseases occurring predominantly in high-income countries and rheumatic heart disease occurring predominantly in low- and middle-income countries. The …

18 years of age All Phase N/A
S Slobodan Micovic

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

MANTRA is a prospective, multiple-arm, multi-center, global, post-market clinical follow-up study. The main objective is to monitor ongoing safety and performance of the CORCYM devices and accessories used for aortic, mitral and tricuspid valvular diseases in a real-world setting. Corcym S.r.l., is a medical device manufacturer with a broad product …

years of age All Phase N/A
W Wang Jian-an, MD,PhD

Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University

We design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective ,treatments and prognosis of Chinese hospitalised adult patients with valvular heart disease.

18 years of age All Phase N/A
Y Yuan Wang, PhD

A Registry Study of Biomarkers in Heart Valve Disease

Valvular Heart Disease, impacting 2.5% of the population, is predominantly observed in the elderly and is on the rise. The primary conditions within this category are Aortic Stenosis and Mitral Regurgitation. These conditions are linked to considerable morbidity and mortality, presenting a formidable challenge in optimizing treatment strategies. Pathophysiology of …

18 - 100 years of age All Phase N/A
H HASCOET SEBASTIEN, PI

European Multicentre Registry of Percutaneous Paravalvular Leak Closure

Paraprosthetic cardiac valve leaks are a progressive complication after after surgical or percutaneous heart valve replacement. These leaks can lead to heart failure and/or life-threatening hemolysis. Percutaneous closure of para-prosthetic leaks has been developed as an alternative to surgery in high-risk patients. These procedures remain technically challenging with a significant …

16 - 110 years of age All Phase N/A

The Prospective LEUVEN Transcatheter Valve Therapy Registry

Assessment of feasibility, safety and outcomes of transcatheter valve interventions

years of age All Phase N/A
O Oga Kuzmina, MD, PhD

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Acquired heart diseases continue to remain one of the most common causes of cardiac mortality and morbidity. In the Russian Federation, open surgery treatment of acquired valvular heart diseases (AVHD) is performed in more than 40 regions by specialists from 92 healthcare organizations. Treating aortic or mitral valve disease using …

18 years of age All Phase N/A

Tricuspid RegUrgitaTion Hamburg Cohort

Tricuspid regurgitation (TR) is frequent and has been directly related to high mortality rates. The pathophysiology of TR is mainly functional as it occurs predominantly in the context of left-sided heart disease, pulmonary hypertension, or atrial fibrillation. Surgery is currently the primary treatment option in patients with functional TR. However, …

18 years of age All Phase N/A

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