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cardiac-disease Clinical Trials

A listing of cardiac-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,908 clinical trials
K Kang An, MD

Efficacy of Self-expandable and Balloon-expandable Valves in Patients With Ascending Aortic Dilation

This study evaluated the efficacy of self-expandable valves and balloon-expandable valves in patients with ascending aortic dilation who undergo transcatheter aortic valve replacement.

65 years of age All Phase N/A
M Mathias Maleczek, MD

MultiCPR: The Influence of Firefighter's PPE on Chest Compressions (MultiCPR3)

The aim of this clinical study is to evaluate the impact of wearing firefighters' personal protective equipment (PPE) on the quality of chest compressions during simulated resuscitation scenarios. The study compares the effects of one-minute versus two-minute intervals for switching the individual performing compressions. How does the clinical trial work? …

18 years of age All Phase N/A
J Joint Research Management Office

A Study to Obtain Imaging Data in 40 Patients Having Transcatheter Aortic Valve Implantation (TAVI)

The aim of this study is to learn if the Computed Tomography scan (CT scan) and heart echo scan TransThoracic Echo scan (TTE or heart echo scan) taken before a Transcatheter Aortic Valve Implantation (TAVI) procedure can be used to predict how the new TAVI valve will perform in the …

18 years of age All Phase N/A
X Xiangbin Pan, Dr

Comparison of Self- and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Undergoing Transcatheter Aortic Valve Replacement: The AAD-CHOICE

This study aimed at comparing the performance of self-expandable valves versus balloon-expandable valves in patients with ascending aortic dilation undergoing transcatheter aortic valve replacement.

65 years of age All Phase N/A
S Savannah Allen, MPH Study Coordinator

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

The primary purpose of this study is to observe reduced access site complications in patients with heavily calcified common femoral arteries requiring Transcatheter Aortic Valve Replacement (TAVR)

18 years of age All Phase N/A
N Nilüfer Kutay GÖKKAYA Prof MD

Preventing Hypoxia in Sedated TAVI: SuperNO₂VA vs. Conventional Oxygen

With increasing life expectancy, the geriatric population continues to grow. According to the Turkish Statistical Institute (TÜİK), the average life expectancy in Turkey between 2021 and 2023 is 77.3 years. As the number of elderly surgical patients rises, optimizing anesthesia care is critical to reducing complications and improving clinical outcomes. …

65 years of age All Phase N/A

Mitral Annular Repair With the CathHELIX™ Transcatheter System in Subjects With FMR

Patients with functional mitral regurgitation classified as moderate to severe (3+) or severe (4+) that are symptomatic (NYHA Class II-IV) will be evaluated for treatment using the CathHELIX Transcatheter Mitral Annuloplasty System.

18 years of age All Phase N/A
X Xiang Chen, Dr

Structural Heart Surgery Assist System for Transcatheter Mitral Valve Edge-to-Edge Repair (TEER).

This trial aims to evaluate the safety and efficacy of the Structural Heart Surgery Assist System in assisting TEER for patients with moderate-to-severe or greater degenerative or functional mitral regurgitation (MR ≥3+). A prospective, multicenter, stratified randomized controlled design with non-inferiority comparison will be used. The experimental group will utilize …

18 years of age All Phase N/A
G Gonzalo Javier Martinez Rodriguez

Capstan Medical TMVR Study: FIH

This study is a prospective, multi-center, non-randomized first in human study to evaluate the safety and feasibility of the Capstan Medical TMVR System for intervention in adults with moderate-severe or greater mitral regurgitation who are not surgical candidates.

18 years of age All Phase N/A
M Mattie Reesman

Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

Early Feasibility Study to evaluate the safety and performance of the Innoventric Trillium™ Stent Graft in the treatment of severe or greater tricuspid regurgitation (TR).

18 - 85 years of age All Phase N/A

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