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cardiac-disease Clinical Trials

A listing of cardiac-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,881 clinical trials
N Nicholas Black, BM BCh

Detecting EARLY Heart Failure in Greater Manchester

Heart failure represents a growing public health problem within the UK and particularly within the North West of England. A major challenge is that heart failure is currently diagnosed too late. The researchers have previously developed a risk calculator that accurately identifies individuals at risk of heart failure admission or …

50 years of age All Phase N/A
Z Zhijun Wu, MD

Risk Evaluation and Management in Heart Failure

This is an prospective study conducted in a Chinese heart failure population. The study investigates the effects of cardiovascular disease risk factors such as lifestyle behaviors,biomarkers and intermediate diseases on heart failure prognosis.

18 years of age All Phase N/A

Samtasu Post-marketing General Drug Use-results Survey in Patients With Volume Overload in Heart Failure.

To confirm the safety of tolvaptan sodium phosphate in patients with volume overload in heart failure.

18 years of age All Phase N/A

Observation of Clinical Routine Care for Heart Failure Patients Implanted With BIOTRONIK CRT Devices

The registry is primarily designed to assess outcome, efficacy and residual safety aspects of CRT based on long-term data from an unselected, real-life clinical set-up. Moreover, the observation of the patient status should help to find possible predictors for HF events and to identify areas of improvement for CRT and …

18 years of age All Phase N/A
D Duk-woo Park, MD

Transpacific TAVR Registry

This registry evaluates the long-term outcome of Transcatheter aortic valve replacement (TAVR) in real-world clinical practice.

19 years of age All Phase N/A
O Okechukwu Ogah, PhD

The Ibadan Acute and Chronic Heart Failure Project

Contemporary studies from South Africa and Nigeria have built on historical reports to demonstrate that the etiology and indeed case profile of acute HF (i.e. more women and younger individuals affected in the prime of their life) is different from high-income countries. As such, HF is now responsible for 7-10% …

18 - 100 years of age All Phase N/A

Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development

The study team will use small pieces of human hearts which are removed as part of a required surgical procedure to study different objectives. One of the objective is how calcium ions pass through the membrane of heart cells in order to tell the heart cell how much force to …

- 20 years of age All Phase N/A
Y Yawei Xu, PhD

Registry for Longitudinal Mortality and Therapy in Patients With Heart Failure

The purpose of this registry is to compile a large clinical database on the medical management of patients hospitalized with acute heart failure, using information collected from hospitals across China.

18 - 90 years of age All Phase N/A
J Jian Li, BS

Artificial Intelligence (AI) Analysis of Synchronized Phonocardiography (PCG) and Electrocardiogram(ECG)

The diagnosis of depressed left ventricular ejection fraction (dLVEF) (EF<50%) depends on golden standard ultrasound cardiography (UCG). A wearable synchronized phonocardiography (PCG) and electrocardiogram (ECG) device can assist in the diagnosis of dLVEF, which can both expedite access to life-saving therapies and reduce the need for costly testing.

18 - 100 years of age All Phase N/A
D Dong-Hyuk Cho, MD

Prognostic Value Of Short-Term Follow-up Biomarkers After Discharge In hOspitalized Patients With Acute Heart Failure

Several surrogate biomarkers including natriuretic peptide(NP), and growth differentiation factor-15(GDF-15) and ST2 has prognostic significance in heart failure(HF), and reductions in its value may predict clinical improvement. However, there are limited data regarding the prognostic value of these biomarkers during short-term follow-up after discharge in acute decompensated heart failure. The …

18 years of age All Phase N/A

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