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eye-disease Clinical Trials

A listing of eye-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 359 clinical trials
h huifang zhou, Doctor

A Study of GenSci098 in Subjects With Active Thyroid Eye Disease

To evaluate the safety and tolerability of single and multiple ascending subcutaneous doses of GenSci098 in patients with thyroid eye disease (TED)

18 - 75 years of age All Phase 1

Evaluation of Performance and Safety of Eye Drops With Hydroxypropyl-methylcellulose and Inositol in Drye Eye Disease

This is a profit, multicentric, prospective, single-arm, open-label, non-pharmacological clinical investigation. Patients with diagnosis of moderate to severe dry eye disease with asthenopia and accommodative effort will receive MERAMIRT®, 1-2 drop per eye 3 times a day for 90 days.

18 years of age All Phase N/A
S Samuel A Alvarez-Falcon, MD

Virtual Reality Visual Field Testing as an Alternative in Childhood Eye Disease

The purpose of this study is to test a new way of measuring the peripheral vision (called a visual field test) using a device which can be worn as goggles rather than being a large instrument the patient must sit at. This new visual field test (called VisuALL) is an …

4 - 21 years of age All Phase N/A
D Dong Wu, Doctor

Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction

Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 270 patients at Beijing Tongren Hospital. All treatments were self-administered by the patients at home after training at the hospital. Patients completed questionnaires at …

18 - 65 years of age All Phase 1/2
A Arnold Leigh, BS

Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction

This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.

18 years of age All Phase N/A
J Jutta Horwath-Winter, Dr

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease

The goal of this interventional investigation is to compare BUFY02 with TRB02 in the treatment of patients with dry eye disease. The main questions it aims to answer are: Is BUFY02 non-inferior to TRB02 in terms of signs of DED? Is BUFY02 non-inferior to TRB02 in terms of symptoms of …

18 years of age All Phase N/A

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

The primary objective of Part A of this study is to investigate the safety and tolerability of AMG 732 after single subcutaneous (SC) doses. The primary objective of Part B of this study is to investigate the efficacy of AMG 732 in participants with Thyroid Eye Disease (TED) after multiple …

18 - 65 years of age All Phase 1

Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease

In this study, the initial tear proteome profiles in Dry Eye Disease (DED) patients, the safety and effectiveness of using an EC certificate DED treatment device in DED management, together with the associated global tear proteome changes, will be investigated.

18 - 65 years of age All Phase N/A
S Sunil Shah, Phd

Impact of Tixel Treatment on Symptoms and Signs in Patients with Dry Eye Disease

This study will examine how a standard Tixel treatment versus a sham treatment for eye wrinkles affects the symptoms and signs of Dry Eye Disease.

18 years of age All Phase N/A

A Trial Investigating Lu AG22515 in Adult Participants With Moderate-to-Severe Thyroid Eye Disease

This trial will evaluate the effects of Lu AG22515 in adult men and women with moderate-to-severe thyroid eye disease (TED). TED is an autoimmune condition closely related to Graves' Disease. In people with TED, the healthy tissue behind and around the eye becomes inflamed and swollen. One of the key …

18 years of age All Phase 1

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