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hernia Clinical Trials

A listing of hernia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 188 clinical trials
b burak nalbant

Dynamic Compliance-Guided Ventilation in Lumbar Surgery

Postoperative pulmonary complications are a frequent cause of morbidity following lumbar stabilization surgery. Conventional ventilation strategies may not adequately reflect intraoperative changes in respiratory mechanics, potentially leading to impaired postoperative pulmonary function. Dynamic compliance-guided ventilation provides a real-time, individualized approach by adjusting ventilatory parameters according to lung compliance. This prospective …

18 - 70 years of age All Phase N/A
V Valeria Mosetti, MD

The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population

Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric population subjected to peripheral nerve block due to Inguinal hernia repair or Flat foot surgery. The present Protocol is …

- 17 years of age All Phase 2
M Mohammed S ElSharkawy, MD

Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy

The aim of this study is to compare spinal and general anesthesia in neonates undergoing herniorrhaphy.

1 - 1 years of age All Phase N/A
M Marion Mandon, PhD

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain

The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and …

18 years of age All Phase N/A
S Sergey S Gordeyev, PhD

Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection

The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair. The main question it aims to answer is: can mesh help prevent hernia? Participants will be divided into 2 groups: with …

18 - 85 years of age All Phase 3
B Bart Jacher

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve …

18 - 80 years of age All Phase 4
S Sergey Morozov, MD, PhD

Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse

This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse

18 - 70 years of age Female Phase 3
V Valerie Schuermans, MD

Cervical Arthroplasty Cost Effectiveness Study (CACES)

To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD). The most commonly used surgical treatment for patients with single- or multilevel symptomatic CDDD is anterior cervical discectomy with fusion (ACDF). However, new complaints of radiculopathy and/or myelopathy commonly develop …

18 years of age All Phase N/A
O Olawumi Olajide, M.B.Ch.B

Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures

The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is: • Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce …

- 15 years of age All Phase N/A
M Mikkel Rasmussen, MD

Precision Treatment of Lumbar Spine Surgery Through Advanced Nerve Root Blockade

The overall purpose of the study is to investigate whether selective spinal nerve root blocks can improve diagnostics of radiculopathy due to lumbar disc herniation (LDH), foraminal stenosis (FS), and recess stenosis (RS), and hence identify the patients that will benefit from surgical intervention.

18 years of age All Phase N/A

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