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Open Heart Surgery Clinical Trials

A listing of Open Heart Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 11 clinical trials
J Jeremy Reeves, BS

Sternotomy PIFB Block in Open Heart Surgery

The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia [MMA]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the …

18 years of age All Phase N/A

Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery

A parallel-group treatment, five-centre, participant and investigator masked, three-arm study to assess the safety and effectiveness of dexmedetomidine or clonidine infusion compared to placebo for the prevention of delirium and cognitive decline in male and female participants aged 70+ scheduled for open heart surgery.

70 years of age All Phase 4

The Effect of Video Game-Based Exercises After Open Heart Surgery

The aim of the study is to investigate the effects of video game-based exercises applied in addition to the cardiac rehabilitation program applied after open heart surgery, on pulmonary function and functional independence in the acute state. After ethics committee approval is received; Patients who volunteer to participate in the …

18 - 65 years of age All Phase N/A
S Salah Eldin Ahmed Abdeluaziz, master

The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery

To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery

years of age All Phase N/A
M Muhammad Saad Yousuf, MBBS, FCPS

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

The goal of this study is to evaluate the effects of steroids on the early postoperative inflammatory response in patients undergoing elective pediatric congenital cardiac surgery, requiring cardiopulmonary bypass (CPB).

1 - 18 years of age All Phase 4

The Effect of Neurophysiological Facilitation Techniques on Health Parameters in Early Stages After Open Heart Surgery

In this study, researchers aimed to investigate effects of neurophysiological facilitation on functional capacity and respiratory parameters of patients who underwent open heart surgery. Do neurophysiological facilitation techniques improve individuals' respiratory parameters more than phase 1 cardiac rehabilitation? Do neurophysiological facilitation techniques improve individuals' functional capacity more than phase 1 …

18 - 75 years of age All Phase N/A
S Shannon Brackett, NP

Propranolol Treatment for Postoperative Chylothorax

Postoperative chylothorax is a serious complication after open heart surgery for pediatric patients with congenital heart disease (CHD). While it was thought to be mechanical injury to the thoracic duct, recent research demonstrated that there are intrinsically abnormal lung lymphatics in CHD patients, and after open heart surgery, the fluid …

7 - 18 years of age All Phase 1/2

A Study Protocol for Research Investigating How Geriatric Risk Assessment and Shared Decision-making Conversations Affect Treatment Decisions and Quality of Life in Patients Eligible for Open-heart Surgery.

The goal of this study is to determine whether intervention by the PRIME clinic influences cardiac treatment decisions, as well as patients quality of life and healthcare utilization. The main questions this study aims to answer are: Does PRIME consultation influence treatment recommendations? Does a personalized treatment plan for cardiac …

70 years of age All Phase N/A
P Peter Raivio, MD, PhD

Spectroscopic Assessment of Intramyocardial Oxygen Saturation During Open-Heart Surgery

The goal of this observational study is to test in the safety and performance of intraoperative myocardial spectroscopic measurement in open-heart surgery patients The main questions it aims to answer are: The Devices can record myocardial spectrometric data for analysis, and How these measures correlate with the occurring events, procedures, …

18 - 90 years of age All Phase N/A
O Osama A Ebrahim, Master

Postoperative Clinical and Neurophysiological Assessment of Patients After Open Heart Surgery

This study aims to investigate postoperative clinical, cognitive and neurophysiological assessment of patients after open heart surgery among sample of Egyptian patients.

60 years of age All Phase N/A

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