osteopenia Clinical Trials
A listing of osteopenia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 177 clinical trials
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
People with Alzheimer's disease are at an increased risk of bone fracture. Some studies have shown that those taking donepezil have a lower rate of bone fractures, but the reasons for this are unknown. The purpose of this study is to measure the effect of donepezil treatment on bone metabolism …
Qualitative Study Exploring the Determinants Involved in the Management of Osteoporosis in Frail Elderly People
The aging population is associated with an increase in the number of elderly people as well as in chronic diseases, particularly osteoporosis and its fracture consequences, which lead to a decline in quality of life and life expectancy. Improved management of osteoporosis would help reduce the morbidity and mortality associated …
Step-down Therapy After Long-term Osteoporosis Treatment
Maintaining bone mineral density (BMD) after discontinuing denosumab (Prolia) is a major clinical challenge, as rapid bone loss commonly occurs when treatment is stopped, especially after more than three years of use. Standard sequential therapy with bisphosphonates such as zoledronic acid (Aclasta) often fails to fully prevent BMD decline, and …
Preserving Geriatric Muscle With an Osteoporosis Medication
Our goal is to demonstrate efficacy of the novel agent Denosumab to improve or preserve muscle health, strength, mobility and function in frail older adults.
Effects of Liposomal Encapsulation on Calcium Powder Absorption and Metabolism
Compared with traditional calcium supplements, liposome calcium can increase the bioavailability of calcium and reduce the waste caused by gastric acid destruction of calcium. This allows calcium to be released slowly in the intestines, reducing the risk of indigestion or other side effects caused by excessive intake at one time. …
The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity
Randomized, placebo controlled prospective trial evaluating the effect of denosumab on insulin sensitivity and muscle strength.
Romosozumab and Denosumab, Alone or Combined, in Postmenopausal Osteoporosis
Osteoporosis is a lifelong chronic condition requiring long-term management. Conventional first-line anti-resorptive therapies often yield slow BMD improvement and may plateau after years of treatment. Recent AACE/ACE guidelines recommend anabolic agents as initial therapy in patients with severe osteoporosis or very high fracture risk; however, even anabolic monotherapy may be …
Effect of Theophylline in Pseudohypoparathyroidism
The study evaluates the effect of theophylline in 100 subjects with Pseudohypoparathyroidism.
Functional and Metabolic Effects of Fonte Fausta® Water on Bone and Muscle Health in Osteoporotic Patients
This clinical study investigates the effects of Fonte Fausta® water on bone and muscle metabolism, as well as quality of life, in patients with osteoporosis or osteopenia, with or without sarcopenia. Conducted as a multicenter, triple-arm trial, it evaluates functional and biochemical markers over 12 months. Patients are randomized into …
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined. Current treatment options do not account for differences between age-related and estrogen deficiency related osteoporosis, because of the need for bone biopsies for determination. This study will …
