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neoplasm-metastasis Clinical Trials

A listing of neoplasm-metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,054 clinical trials
C CHAO-HUNG WANG, MD

Phenylalanine-free Diet for Patients With Secondary Hyperphenylalaninemia in ICU

Hyperphenylalaninemia is not only present in patients with congenital phenylketonuria. In adults with critical illness, hyperphenylalaninemia is noted in some patients and is associated with high mortality rate. Hyperphenylalaninemia can cause metabolic acidosis, brain dysfunction, and metabolic disturbance. The investigators would like to see whether the phenylalanine-free milk for congenital …

20 years of age All Phase N/A
D Dawn Carini

Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)

To demonstrate that microwave ablation (MWA) of up to 3 hepatic metastases, each with a maximum diameter of ≤ 2.5 cm will result in a 2-year local progression free survival of at least 90%. This is a standard of care (SOC) study.

18 years of age All Phase N/A
L Lizza Hendriks, MD, PhD

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

This study will evaluate whether the combination of sacituzumab govitecan (SG) and bevacizumab will result in shrinkage of brain metastases from patients with non-squamous non-small cell lung cancer (NSCLC), with disease progression on chemotherapy and immunotherapy.

18 years of age All Phase 2
S Sindhu Reddy

Embolization for the Treatment of Heel Pain Secondary to Plantar Fasciitis

This study evaluates the feasibility and safety of using Lipiodol (ethiodized oil) as an investigational embolic agent for treating pain caused by plantar fasciitis. Participants will undergo a minimally invasive procedure called plantar fascia embolization (PFE) to reduce inflammation and pain in the affected area. The study aims to assess …

22 - 100 years of age All Phase N/A
L Liao Wei

FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis

Try FOLFOX-HAIC combining bevacizumab or cetuximab for initially unresectable colorectal liver metastasis patients to increase the conversion to resection rate to improve long-term survival outcomes

18 - 75 years of age All Phase 2
Z Zhenzhen Liu, PhD

Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation

To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia

18 - 14 years of age All Phase N/A

Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Norfloxacin versus Norfloxacin with Itopride in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

years of age All Phase 3
J Jakob Kirkegård, MD, PhD

Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation

To examine radio frequency ablation as a treatment supplement to stimulate immunogenicity and improve survival for patients undergoing curative-intent surgery for colorectal liver metastases.

18 - 99 years of age All Phase N/A
N Nicholas Tedesco, MD

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

The goal of this clinical trial is to find out if removing and replacing part of the hip bone works better than using metal hardware to stabilize the bone in patients whose cancer has spread to the hip. The main questions are: Does removing and replacing part of the bone …

18 years of age All Phase N/A
E Emily Michelich

A Dose Escalation Study of AV-380 in Metastatic Cancer Patients With Cachexia

This open label ascending dose study is designed to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of AV-380 in metastatic cancer patients with Cachexia. AV-380 is an immunoglobulin (Ig) G1 monoclonal antibody (mAb) intended to bind circulating human growth differentiation factor 15 (GDF-15), a cytokine involved in cancer-induced …

18 years of age All Phase 1

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