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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,778 clinical trials
A Asma A Alqahtani, B.S.C

Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Randomized control trial to examine the immediate effect of isometric exercise on pressure pain threshold (PPT) in adults with chronic low back pain. The secondary aim of this study was to investigate the acute effects of isometric exercise on clinical pain intensity.

18 years of age All Phase N/A
I Irene Torres-Sánchez, PhD

Effects of Pain Neuroscience Education and Virtual Reality in Patients with Chronic Low Back Pain

The objective of our study is to evaluate the effects of a therapeutic intervention including 1-hour of pain neuroscience education session, 30-minutes of exposure to exercise with virtual realit and therapeutic exercise in patients with chronic low back pain.

18 - 65 years of age All Phase N/A

Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?

Conditioned pain modulation (CPM) a measure of the effectiveness of the descending pain pathway and therefore a measure of the body's ability to perform endogenous analgesia. In subjects with normal function of the descending pain pathway, the net-effect during CPM testing is anti-nociceptive, or inhibition of the ascending pain pathway. …

18 - 64 years of age All Phase N/A
K Keith M Vogt, MD, PhD

Sevoflurane's Effect on Neurocognition Study

The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose sevoflurane. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will occur over 2 …

18 - 59 years of age All Phase 1
F Filomena RG Galas

Evaluation of Virtual Reality for Reducing Opioid Use After Cardiac and Thoracic Surgery

This clinical trial aims to evaluate the efficacy of virtual reality (VR) as an adjunctive therapeutic method to reduce opioid consumption during the postoperative period of cardiac and thoracic surgeries. It is a single-center, prospective, randomized trial that will include 60 patients aged 16 to 40 undergoing surgeries such as …

16 - 40 years of age All Phase N/A

Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery

The objective of this study will be to evaluate if photobiomodulation (FBM) can reduce postoperative pain in patients who will undergo endodontic surgery. For this randomized, controlled and double-blind clinical study, 34 patients without comorbidities who need endodontic surgery in the upper jaw (15 to 25 teeth) will be recruited. …

18 - 70 years of age All Phase N/A
B Basak Cigdem Karacay

Virtual Reality in Patients With Knee Osteoarthritis

One of the main challenges facing the therapist in the treatment of adhesive capsulitis is to motivate the patient throughout conventional therapy. As noted in a recent review, individuals are more interested in leisure activities rather than performing repetitive tasks during therapy. Virtual reality (VR) is a three-dimensional computer-aided programme …

40 - 85 years of age All Phase N/A

Nitrous Oxide Neuroimaging

The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose nitrous oxide. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will occur over …

18 - 59 years of age All Phase N/A
J Jordan Wood

The Ability of Chronic Pain Patients to Self-diagnose Their Chief Source of Low Back Pain

The investigative team will provide 27 slides with bullet points and images of pain referral patterns for different causes (e.g., herniated disc, facet joint arthritis) for patients seen for a new visit with a chief complaint of chronic low back pain. This material is all publicly available but has been …

18 years of age All Phase N/A
E Emrah Afsar, Phd

Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With Nosiplastic Pain

The aim of our study was to determine the effectiveness of desensitisation and pain neuroscience education in a group of patients with mixed phenotype pain (neuropathic and nosiplastic).

18 - 65 years of age All Phase N/A

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