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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,478 clinical trials
A Amélie Apinis-Deshaies Research Coordinator

Cannabidiol After Multi-Trauma for Pain and Opioid Therapy

The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex on CBD treatment response. To this end, this research protocol proposes a comprehensive translational approach including …

18 - 70 years of age All Phase 2
M Michael Shalaby, MD

Genicular Nerve Block for Knee Pain in the ED

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

18 years of age All Phase N/A

Efficacy of Suprascapular Radiofrequency Ablation in Hemiplegic Shoulder Pain

Stroke, one of the most important causes of disability and death in the world, is an acute focal deficit of the central system caused by vascular origin such as cerebral infarction, intracerebral haemorrhage and subarachnoid haemorrhage. Hemiplegic shoulder pain, which is one of the most common complications after stroke, is …

18 years of age All Phase N/A
M Madiha Ali, MSOMPT

Comparison of Gongs and Kaltenborn Mobilization on Neck Pain

The aim of this randomized controlled trial is to find the effect of Gongs mobilization in comparison with Kaltenborn mobilization on mechanical neck pain , range of motion and proprioception.A randomized control trial that will include total 44 participants. The first group will receive Gongs mobilization along with conventional therapy …

18 - 65 years of age All Phase N/A
A Anders H Springborg, MD

Cryoneurolysis for Acute Postoperative Pain Following Total Knee Arthroplasty

Cryoneurolysis is a regional anaesthetic technique that works by freezing peripheral sensory nerves. This technique can potentially provide analgesia after total knee arthroplasty (TKA). However, the technique is expensive and comprehensive. Pain 24 hours after surgery is associated with high amounts of late acute pain. Therefore, the aim of the …

18 years of age All Phase N/A
K Kliment Gatzinsky, MD, PhD

Placebo Effect In Spinal Cord Electrical Stimulation for Pain

Objective: To evaluate if spinal cord stimulation (SCS) performs better than placebo (no stimulation) in the long term to reduce persistent neuropathic leg pain refractory to medication and other conservative treatments in patients who have undergone lumbar spinal surgery. Study design: Multicenter, double blind, randomized, sham-controlled trial. After a positive …

18 - 70 years of age All Phase N/A
P Philippe De Vloo, prof.dr.

Neuromodulation for Central Post-stroke Pain: Mechanism, Safety and Outcome

Central post-stroke pain (CPSP) is an often pharmacorefractory type of neuropathic pain that develops in 8% of stroke patients. CPSP has been treated with three distinct types of neuromodulation (deep brain stimulation of the sensory thalamus (Vc-DBS), motor cortex repetitive transcranial magnetic stimulation (M1-rTMS), and motor cortex stimulation (MCS)), but …

18 - 70 years of age All Phase N/A
J Jee Youn Moon, M.D.

The Effect of Virtual Reality Experience on Infusion-related Pain

This clinical trial aims to analyze the effect of virtual reality experience on infusion-related pain with lumbar epidural catheterization.

20 years of age All Phase N/A
A Abdallah A Eldisouky

L-carnitine in Modulating Pain and Inflammation in Rheumatoid Arthritis

This study aims at evaluating the possible efficacy and safety of L-carnitine in rheumatoid arthritis via targeting Jak/STAT pathway and TGF-β1

18 - 70 years of age All Phase 3
U UIC Universidad Internacional de Catalunya

Efficacy of Air-polishing on Pain Perception and Compliance Rate

Implants have become a popular and widely used treatment option for treating partial and total edentulism. As the number of implants placed increases, so does the incidence of peri-implant mucositis and peri-implantitis. Placing patients under SPT/maintenance care has been shown to prevent and treat such conditions. Despite SPT's importance in …

21 - 80 years of age All Phase N/A

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