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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials

Brief Mindfulness Intervention for Chronic Pain in Ukraine

This is a pragmatic randomized controlled trial comparing a single 15-minute mindfulness-based intervention to usual care for patients with chronic pain in Ukraine being seen in a pain clinic.

18 years of age All Phase N/A
A Aminata Bicego, PhD

Self-induced Cognitive Trance for Chronic Pain Management

The need to find complementary approaches, based on a holistic perspective of the human being, takes on its full meaning in a political context that recommends efficient health programs. Self-induced cognitive trance is one of these complementary approaches, which induce a non-ordinary state of consciousness. The aim of this work …

18 - 70 years of age All Phase N/A
J Joao De'Aquino, M.D.

Cannabidiol in Opioid Use Disorder and Chronic Pain

This is a double-blind, randomized, placebo-controlled cross-over human laboratory study with a duration of approximately 3 weeks, during which participants will come to the testing site for a total of five times: one initial screening session, and four experimental sessions where study medication, Cannabidiol (CBD) will be administered, separated by …

18 - 70 years of age All Phase N/A
Γ Γιωργος Πλουταρχου

The Effectiveness of Cognitive Functional Therapy in Adults With Chronic Neck Pain

The aim of this study was to compare the effectiveness of Cognitive Functional Therapy compared with Conventional Therapy in treating adults with chronic neck pain

18 - 64 years of age All Phase N/A

Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain

One in five Canadians live with chronic pain, defined as pain that lasts longer than 3-months. Living with chronic pain has a detrimental impact on physical health, emotional health, and quality of life. Current treatments rarely result in pain relief and often do not meaningfully improve physical or emotional function. …

18 years of age All Phase 2/3

From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects

This is a multicenter prospective study of patients who currently have stably implanted spinal cord simulators. Patients will be randomly assigned to turn on or off their spinal cord stimulators for two week intervals up to six weeks after enrollment, and on the final day of study participation, for one …

18 - 80 years of age All Phase N/A
F Fady Girgis, MD

Neuromodulation Parameter Efficacy

The objective of this study is to determine the efficacy of neuromodulation using various stimulation paradigms in the treatment of several disorders including chronic pain.

18 - 100 years of age All Phase N/A

The Role of Brain Dopamine in Chronic Pain

Chronic pain is associated with plasticity in the brain limbic system composed mainly of the amygdala, hippocampus, ventral striatum, and cingulate cortex (ACC) /medial prefrontal cortex (mPFC). These brain areas, especially the ventral striatum, receive dopaminergic input from the ventral-tegmental area (VTA). Although there is a significant literature now showing …

18 years of age All Phase 2

IPRP Repeated Transcranial Magnetic Stimulation (rTMS)

Severe chronic pain is defined as pain persisting for three months or more that significantly impacts daily functioning. It is highly prevalent, occurring in 100,000 to 160,000 youth. If left unmanaged it can lead to persistent pain and mental health problems in adulthood, posing enormous costs to society ($7.2 billion …

10 - 18 years of age All Phase N/A
S Sophie Rosenkjær

Effects of Spinal Cord Stimulation

The goal of this interventional study is to test effects of spinal cord stimulation in patients receiving treatment for their chronic pain. The main question of the study is: • What is the effect of spinal cord stimulation when compared to placebo? Participants will rate their pain with their usual …

18 - 99 years of age All Phase N/A

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