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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,778 clinical trials
M Merve Beke, MSc

The Effect of Chewing Gum and Hot Compresses on Gynecologic Oncologic Surgery

The passage discusses the recovery of gastrointestinal (GI) function after abdominal surgery and the potential impact on patient comfort. After surgery, small bowel activity typically returns to normal within a few hours, gastric activity within 24-48 hours, and colonic activity within 48-72 hours. However, the delayed mobility of the GI …

18 years of age Female Phase N/A
J Jane Kelly

A First in Human Study of TT5 in Single and Multiple Ascending Doses in Healthy Volunteers and Surgical Patients

This study is a First in Human, three-parts, double-blind, randomized, placebo-controlled, single and multiple ascending dose study. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of TT5 at different doses in healthy and surgical participants.

18 - 55 years of age All Phase 1
K Kudret Dogru, Prof

Does the TAP Block Work Better Than the TFP Block for Relieving Pain

Regional anesthetics, nerve blocks, and interfascial blocks are becoming more common in many types of surgery to help with pain after surgery. Most clinicians concur with the importance of reducing postoperative pain scores and facilitating early discharge. The transversalis fascia plane block (TFP) and transversus abdominis plane block (TA), which …

18 - 70 years of age Male Phase N/A
K Ke Ma, PhD

Effects of Virtual Reality (VR) Based Distraction and Relaxation Therapy on Moderate and Severe Pain

This is a prospective, single-arm, open, single-center clinical study. This study is a pilot study to explore the use of VR based distraction and relaxation therapy as an adjunctive analgesic method for Chinese patients with moderate to severe pain. After screening, patients with moderate to severe pain who meet the …

18 years of age All Phase N/A
R Rachel Henning

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants. Deep Inferior Epigastric Perforator (DIEP) flaps are the gold standard for autologous breast reconstruction . Effective pain control following surgery …

18 - 70 years of age Female Phase N/A
D David T Field, PhD

The Effects of Vitamin B6 Supplementation on Pain Thresholds and Tolerance

This clinical trial aims to explore the effect of Vitamin B6 supplementation on pain thresholds and tolerance in healthy adults using thermal and electrical stimulation. Researchers will compare a placebo group to high-dose Vitamin-B6 to see if vitamin B6 increases pain thresholds and tolerance.

18 years of age All Phase 1
M Melek Nur GÜZEL

Comparison of Two Methods in Pain Caused by Orogastric Tube Placement in Preterm Newborns

Aim : This study will be conducted to determine the effect of breast milk and knitted octopus in reducing pain caused by routine orogastric tube insertion in preterm newborns. Method : This study was planned as a randomized controlled trial. The study group will consist of 66 preterms with a …

32 - 34 years of age All Phase N/A
F Fang Luo, M.D.

Pre-emptive Scalp Infiltration with Triamcinolone Acetonide Plus Ropivacaine for Post-Craniotomy Pain in Children

At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the other hand, the particularity of craniotomy adds (such as consciousness obstacle, sleepiness, et al) disturbance to the pain assessment …

2 - 12 years of age All Phase 4
J Jan Stefaniak, M.D.

Correlation of Pain Intensity Measurements in Healthy Volunteers Exposed to Unpleasant Stimuli

Pain is an unpleasant sensory and emotional phenomenon that can be caused by tissue damage or potentially harmful stimuli. Pain is by definition a subjective phenomenon, and everyone experiences it differently, which creates problems in its assessment and treatment. There are many ways to measure pain, both through patient self-report …

18 - 40 years of age All Phase N/A
S Sena Dilek Aksoy, Ph.D.

Nonpharmacological Method for Relief During Episiotomy Repair

The study was planned as a randomized controlled trial to evaluate the effect of reflexology on perceived perineal pain during episiotomy repair. The research will be carried out with participants who gave birth vaginally at Darıca Farabi Training and Research Hospital between July and December 2024. The research will be …

18 - 35 years of age Female Phase N/A

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