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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
M Marta Cenac-Mehedinti

A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).

The purpose of this clinical trial is to determine if women with dysmenorrhea demonstrate an increased musculoskeletal and autonomic nervous system response to a painful visceral stimulus compared to controls. A secondary aim is to determine if interoceptive awareness moderates this relationship. The designed methodology aims to elucidate the intricate …

18 - 35 years of age Female Phase N/A
E Emilie Miley

Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention

This project is a single-site, two-arm, randomized controlled trial investigating whether providing patients in an orthopedic clinic waiting room an audio-recorded mindfulness practice decreases their pain relative to an injury management control condition.

18 years of age All Phase N/A
N Nuran Eyvaz

Transcranial Magnetic Stimulation Therapy in Neuropathic Painful Spinal Cord Injury Patients

The aim of our study is to investigate the effect of high-frequency Repetitive Transcranial Magnetic Stimulation(rTMS) therapy applied to the dorsolateral PFC (DLPFC) area on neuropathic pain in patients with spinal cord injury. In this area, there are very few studies on the effectiveness of rTMS treatment added to medical …

20 - 70 years of age All Phase N/A
M Michael Lankhorst, MD

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

The study involves permanent spinal cord stimulator (SCS) placement in participants with peripheral arterial disease (PAD) and painful diabetic neuropathy (PDN). Participants will be between 19 and 89 years old, have diabetes with symptoms of neuropathy, and have a starting pain level of at least 5 cm on a visual …

19 - 89 years of age All Phase N/A
B Brendan Sullivan

Effects of Dronabinol in Opioid Maintained Patients

Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of …

18 - 70 years of age All Phase N/A

Effect of Virtual Reality and Music Therapy on Pain Relief in OPH Operations

Outpatient hysteroscopy can serve as a diagnostic procedure to evaluate for abnormal uterine bleeding, such as menorrhagia or postmenopausal bleeding. This study focuses on the therapeutic aspect of outpatient hysteroscopy, such as myomectomy, polypectomy, intrauterine adhesiolysis and removal of lost intrauterine devices, etc. Apart from the conventional polyp scissors and …

18 - 80 years of age Female Phase N/A
M Mehmet Kurkcu

Musical Intervention During IV-line Placement in Neonates

The goal of this clinical trial is to test the effect of music in reducing the pain felt by newborn children during an intravenous line procedure. An intravenous line is a small tube brought into a vein by using a needle. The main questions it aims to answer are: Does …

years of age All Phase N/A
L Luis GARCIA-LARREA, MD

Traumatic Long-term Memory of Pain in Humans

Few studies have focused on understanding the mechanisms underlying pain memory in humans. Thus, this project aims to investigate the link between pain memorisation and memorisation of the associated context by addressing the issue of pain conditioning. The study is composed of two successive parts: one pilot then one experimental. …

18 - 50 years of age All Phase N/A

Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination

Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, the investigators will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, decision-making, and activation …

21 - 45 years of age All Phase N/A
L Lauren E Nieder, MSPH

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, we will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, and decision-making.

45 - 85 years of age All Phase N/A

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