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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,817 clinical trials
T Trevor North, MD

Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty

Participants are being invited to take part in a research study about pain control after total knee replacement surgery (also called total knee arthroplasty or TKA). The goal of this study is to see if a new long-acting medication, called Zynrelef, can control pain after surgery as well as or …

18 years of age All Phase 4

Effect of Acupressure on Postoperative Pain After Laparoscopic Totally Extraperitoneal Inguinal Hernia Repair

This randomized, sham-controlled clinical trial aims to evaluate the effect of acupressure on postoperative pain following laparoscopic totally extraperitoneal (TEP) inguinal hernia repair. A total of 90 participants will be randomly assigned to one of three groups: standard postoperative care alone (control group), true acupressure plus standard care, or sham …

18 - 75 years of age All Phase N/A
G Gizem Ergezen, MSc

Effects of Physiotherapy Approaches on Biopsychosocial Outcomes in Chronic Non-Specific Neck Pain

Chronic non-specific neck pain (CNSNP) is a widespread musculoskeletal condition leading to pain, disability, and impaired quality of life. Due to its multifactorial nature involving biomechanical, sensorimotor, and psychosocial aspects, various rehabilitation interventions have been recommended. However, there is a lack of direct evidence comparing structured exercise, sensorimotor training, and …

18 - 65 years of age All Phase N/A

Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL

Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals. Despite advancements in surgical techniques, optimal post-operative rehabilitation remains critical for successful functional recovery, minimizing re-injury risk, and restoring pre-injury performance levels

18 - 45 years of age All Phase N/A
M MUHAMMAD ASIF JAVEED, MS-PT

Myofascial Release and Dynamic Cupping in Children

Neck pain is a common musculoskeletal disorder that significantly affects quality of life and daily activities, with an annual prevalence of 30-50% worldwide. This randomized clinical trial aims to compare the effects of myofascial release therapy and dynamic cupping on neck pain and posture in school-based children aged 7-12 years. …

7 - 12 years of age All Phase N/A
D Deniz Demirci, PhD

Effects of Muscle Energy Technique on Neck Disability and Cervical Range of Motion in Individuals With Non-Specific Neck Pain

This study aims to investigate the effect of the Muscle Energy Technique on neck disability level and cervical range of motion in individuals with non-specific neck pain. The study will be conducted at Avicenna International Hospital in Istanbul. Participants with non-specific neck pain will be included in the study. The …

18 - 65 years of age All Phase N/A
D Didem Bozak

End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves

Aim of the EndPaRL study is to compare the efficacy and effectiveness of the two techniques utilizing sharp straight conventional radiofrequency needle with a trident needle for radiofrequency neurotomy of Cervical Medial Branch Nerves (CMBNs), in patients presenting with chronic, moderate-to-severe, neck pain due to cervical zygapophyseal joint osteoarthritis, as …

18 - 85 years of age All Phase N/A
Y Yuan Wang, M.D.

Magnetic Resonance Imaging Study on Young and Middle-aged Patients With Cervical Spondylotic Pain

Cervical and shoulder pain in young adults is commonly caused by intervertebral disc degeneration, bulge or herniation. Disc degeneration includes the synthetic and degradative imbalance of myxoid matrix, degeneration of annulus collagen, and decrease of water content in nucleus pulposus. A few patients with cervical degeneration had moderate to severe …

18 - 50 years of age All Phase N/A
I Iosune Salinas-Bueno, PhD

Therapeutic Exercise Through Exergames on Mobile Devices for Cervical Rehabilitation

The objective of this study is to determine whether performing cervical therapeutic exercises using a serious game through a mobile application enhances treatment adherence compared to performing the same exercises at home following standard practice.

18 - 70 years of age All Phase N/A
S Soad A. Mohamad, phd

Effect of Dose Variations of High-Power Laser Therapy on Patients With Nonspecific Cervical Pain

Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population. Neck pain often results in considerable discomfort and functional limitations, impacting individuals' quality of life and ability to perform daily tasks. Estimates suggest that up …

18 - 40 years of age All Phase N/A

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