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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,817 clinical trials
K Kristian K Petersen, Dr. Med

Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to: Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation Participants will …

18 - 45 years of age All Phase N/A
A Amanda Higgins, M.E.d

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord injury.

18 years of age All Phase N/A
N Nadine ATTAL

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain

Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood. Stroke pain is traditionally considered to be of central origin and related to changes in the spinal cord and/or brain nociceptive systems. …

18 years of age All Phase 3
K Karisma Kothari, MD

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL). Therapeutic virtual reality (VR) has emerged as a promising and evidence-based treatment modality for cancer pain. Users of VR wear a …

18 - 99 years of age All Phase N/A
D Della Molloy-Daugherty, PhD

Active Music-Based Intervention in Patients With Chronic Low Back Pain

The goal of this clinical trial is to learn if active music-based intervention works to treat patients with chronic low back pain. The main questions it aims to answer are: Does active music-based intervention improve cognitive function? Does active music -based intervention improve sensitivity to stimuli? Does active music-based intervention …

18 - 65 years of age All Phase N/A
G Gunther Landmann, Dr. med.

Virtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI

About 70% of people with a spinal cord injury in Switzerland have chronic pain that lasts more than 3 to 6 months. This pain can be caused by muscle or joint problems, or by nerve damage (neuropathic pain). Neuropathic pain is often hard to treat, and current treatments may cause …

18 - 75 years of age All Phase N/A
K Konstantinos Kalimeris MD, PhD, Associate Professor of Anesthesiology

Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)

Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches. Although acupuncture has also shown analgesic effectiveness, its variability and reliance on practitioner skill limit its universal introduction into Western …

35 years of age All Phase 0
S Shuangjie Wu

Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea

Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects. Methods: A total of 42 IBS-D patients were recruited and randomly assigned (1:1) to the sham rTMS or the rTMS group. A nested cohort of …

18 - 75 years of age All Phase N/A
A Antonio Amodeo, MD

VIrtual Reality Induced Pain and anxiEty Relief in Outpatient UROlogical Procedures

Though the efficacy of VRH is documented in various outpatient urological procedures and has provided promising preliminary information in prostate biopsy, its systematic use in urology remains poorly studied. Considering the potential of invasive urological procedures to induce significant patient discomfort, the application of innovative immersive approaches, such as those …

18 - 99 years of age All Phase N/A
A Ayesha Aslam, DPT

Thoracic Thrust With Cervical Non-Thrust Mobilization in Mechanical Neck Pain

This study is a randomised controlled trial and the purpose of this study is to determine the effects of thoracic thrust with cervical non-thrust mobilization in mechanical neck pain on components such as pain, thoracic range of motion, kyphotic angle, craniovertebral angle and proprioception.

20 - 40 years of age All Phase N/A

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