pain Clinical Trials
A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 2,757 clinical trials
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants. Participants will be randomized to (1) a moderate dose ketamine, (2) moderate dose ketamine +Mg, or (3) a magnesium control …
Comparative Effects of Perturbation and Functional Stabilization Training on Patellofemoral Pain Syndrome
The main objective of this study is to determine the comparative effects of perturbation and functional stabilization training on pain, balance, and performance in athletes with patellofemoral pain syndrome(PFPS). Patellofemoral pain syndrome is one of the well known causes of anterior knee joint pain. Proximal and distal joint muscle imbalances …
Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients
This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage chronic knee pain in older adults with Alzheimer's Disease and Related Dementias (ADRD). Chronic knee pain is prevalent among individuals …
Oral Hyoscine vs. Topical EMLA vs. Placebo for Pain Reduction During Hysterosalpingography
This randomized, double-blind, placebo-controlled, will evaluate whether oral hyoscine butylbromide or topical eutectic lidocaine-prilocaine (EMLA) spray reduces pain during hysterosalpingography (HSG) compared with placebo
Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain
This is an open label, 2-part early phase study designed to evaluate the safety, pharmacokinetics, radiation dosimetry, and preliminary efficacy of TLX090-Tx in patients with painful bone metastases.
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
The goal of this clinical trial is to learn if intravenous citrulline works to treat acute pain in hospitalized patients with sickle cell disease. It will also learn about the safety of intravenous citrulline. The main questions it aims to answer are: Does intravenous citrulline decrease the duration of sickle …
Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain
Chronic lower back pain is a significant cause of disability, affecting 21-68% of people 60 years of age and older (source). Of these cases, 15-30% are attributed to posterior sacroiliac joint complex (PSIJC) pain (source), making it a target for treatment. Peripheral Nerve Stimulation (PNS) is a procedure that involves …
The Effects of Drama Activities on Nursing Students' Attitudes Towards Pain Assessment
Title The Effect of Drama-Based Education on Nursing Students' Attitudes Toward Pain Assessment: A Randomized Controlled Trial Abstract This randomized controlled trial aims to investigate the effect of drama-based education on nursing students' attitudes toward pain assessment. The study will be conducted during the 2025-2026 academic year at Necmettin Erbakan …
Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery
This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries. The research compares pain relief in two groups: one receiving a combination of bupivacaine and dexmedetomidine via a transversus abdominis plane (TAP) block, and the other receiving bupivacaine alone. The study aims …
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD). The …
