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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
J Jillian Baker, RN

Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease

The goal of this clinical trial is to learn if intravenous citrulline works to treat acute pain in hospitalized patients with sickle cell disease. It will also learn about the safety of intravenous citrulline. The main questions it aims to answer are: Does intravenous citrulline decrease the duration of sickle …

4 - 21 years of age All Phase 2
A Aisha Razzaq, MSPT-OMPT

Comparison of Core Stabilization and Neuromuscular Facilitation Exercises for Lowback Pain Prevention

Low back pain (LBP) is a leading cause of disability worldwide, particularly affecting individuals in occupations that demand prolonged sitting or standing, such as healthcare professionals. The nature of their work often involves sustained postures, physical exertion, and repetitive movements, which compromise core muscle function and neuromuscular control, increasing the …

20 - 45 years of age All Phase N/A

Local LevoBupivacaine for Pain Relief After Endoscopic Submucosal Dissection for Esophageal Lesions

Endoscopic submucosal dissection (ESD) is commonly performed for (pre)cancerous lesions in the esophagus. Following ESD, post-procedural chest pain is seen in many patients. Studies have shown that local bupivacaine (BP) into the residual submucosal layer of the resection wound after gastric ESD could reduce post-procedural pain rates effectively. Levobupivacaine (LB) …

18 years of age All Phase N/A

PBMT in Providing Temporary Relief of Low Back Pain of Musculoskeletal Origin

The goal of this clinical trial is to evaluate the effectiveness of PBMT for adjunctive use in providing temporary relief of minor chronic low back pain of musculoskeletal origin. The main questions it aims to answer are: (i) Is PBMT able to decrease pain intensity in patients with chronic low …

18 - 65 years of age All Phase N/A
K Kai Yu Ho

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

This study sought to investigate whether modulation of cortical excitability of the gluteal musculature, via tDCS paired with exercise, will reduce the amount the knee caves in during functional tasks in individuals with PFP. The objective is the explore if having tDCS target the area of the brain controlling hip …

18 - 45 years of age All Phase N/A

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

The purpose of this study is to investigate the efficacy of three different modalities of post-operative pain control in parturient with opioid use disorders. The investigators aim to determine whether the different approach utilized show better outcomes with pain management and if there are any association with reduction of symptoms …

18 - 40 years of age Female Phase N/A
A Anna Dalmau-Roig, MD

Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain

PAINDOC is a treatment program that includes 4 disciplines that, separately, have demonstrated their effectiveness in the treatment of chronic low back pain: education in pain neuroscience, therapeutic education (Empowered Relief®), psychotherapy based on cognitive-behavioral therapy and therapeutic exercise. The primary objective of the study is to evaluate the effectiveness …

18 years of age All Phase N/A
H Hatice Dönmez, PhD

Virtual Reality on Pain and Fear Levels of Children With Primary Immunodeficiency

In this study, it is aimed to investigate the effect of virtual reality and tablet video viewing intervention on pain and fear levels and vital signs of children during peripheral venous catheter placement for intravenous immunoglobulin (IVIG) administration.

4 - 11 years of age All Phase N/A
J Jonathan Greenberg, PhD

Feasibility Testing of the "Face-Forward-Web" Program for Chronic Orofacial Pain

The goal of this study is to conduct a feasibility open pilot study (N=Up to 20) with exit interviews to assess the feasibility, acceptability, and credibility of the study protocol and Face-Forward-Web; a web-based mind-body intervention for adult patients with COP. Deliverables: [1] Adapt and refine open pilot protocol, patient …

18 - 18 years of age All Phase N/A
S Sabrina Sanchez, MD

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer, post-traumatic stress disorder, and depression. Studies have also demonstrated that even in healthy adults, the presence …

18 years of age All Phase N/A

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