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inflammation Clinical Trials

A listing of inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 499 clinical trials

A Study of Ear Nerve Stimulation to Treat Eye Inflammation

The purpose of this study to find out whether a device that delivers mild electrical stimulation to the ear (transcutaneous auricular vagus nerve stimulation, or taVNS) can reduce inflammation in the eye in people with ocular inflammatory conditions. The device is called the Cymbathera One System.

18 years of age All Phase 1
M Michael Osborne, MD

The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease

This study aims to evaluate the effect of 8 weeks of a stress reduction intervention on atherosclerotic plaque inflammation in adults with stable coronary artery disease, as quantified by positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in individuals with increased psychosocial stress.

45 - 65 years of age All Phase N/A
W Woo Ri Chae, MD MSc

Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation

A large body of evidence on depression heterogeneity point to an "immunometabolic" subtype characterized by the clustering of immunometabolic dysregulations with atypical behavioral symptoms related to energy homeostasis. Motivational and motor impairments reflected by symptoms of anhedonia and psychomotor retardation in major depression are closely related to alterations in energy …

18 - 65 years of age All Phase N/A
A Abraham Rutgers, MD-PhD

eGPA and Local Inflammation Within the Ear, Nose and Throat Area

Rationale: Eosinophilic Granulomatosis with Polyangiitis (eGPA), eosinophilic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) are airway diseases where eosinophils and interleukine-5 are involved in the pathogenesis. eGPA differs from the other diseases with respect to involvement of other organs. The investigators hypothesize that nasal microbiome dysbiosis with a central …

18 years of age All Phase N/A
M Mona Mashayekhi, MD

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Obesity is associated with increased cardiometabolic disease risk due, in part, to heightened chronic inflammation arising from adipose tissue. There are no current targeted therapies to prevent or reverse the chronic inflammation of obesity, and a better understanding of these inflammatory pathways in humans is key to future therapeutic interventions. …

18 years of age All Phase 1/2

Vaccine Immunity and Inflammation in the Aging Person Living With HIV

This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.

18 years of age All Phase 4
C Claire Goebel, B.S.

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in 2007. Prevalence of ever and current e-cigarette use is highest among teenagers and young adults with 16-28% of this …

18 - 24 years of age All Phase 0
S Sasa Rajsic, MD, PhD

Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions

The goal of this prospective observational study is to evaluate the most appropriate anticoagulation monitoring tool for unfractionated heparin (UFH), by comparison of different monitoring modalities in relation to adverse events occurrence (thrombosis/bleeding). The main study questions are: What is the most appropriate anticoagulation monitoring tool (ACT, aPTT, viscoelastic tests …

18 years of age All Phase N/A
N Nicolette C Bishop, PhD

EXercise Therapy in Axial SpA, Inflammation and Biologic Therapy (ExTASI-B)

The goal of this randomised controlled trial study is to investigate whether exercise (brisk walking, equal to 13 on a rating of perceived exertion scale; somewhat hard) can be used as an adjuvant therapy for people living with axial spondyloarthritis and taking biologic medications to further improve their quality of …

18 years of age All Phase N/A
P Pei-Chen Chang, MD, Master

Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression

This is a 12 week double blind RCT aimed to investigate the role of omega-3 fatty acids in patients with major depressive disorder

13 - 18 years of age All Phase N/A

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