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anesthesia Clinical Trials

A listing of anesthesia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 557 clinical trials

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm …

65 - 90 years of age All Phase N/A
A Abeera Zareen, MBBS, FCPS

Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients

Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it blocks nerves originating from spinal cord providing both anesthesia and analgesia. This technique avoids …

16 - 40 years of age Female Phase 4
D Doaa Ali Gamal

Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).

18 - 70 years of age All Phase N/A
A Asli Dönmez, Full Prof

Effect of Social Stories on Anesthesia Compliance in Children With Autism

Children with Autism Spectrum Disorder (ASD) frequently experience heightened anxiety and reduced cooperation during the perioperative period, which can complicate anesthesia induction and negatively affect procedural safety and efficiency. Non-pharmacological behavioral preparation methods that enhance predictability and understanding of medical procedures may improve anesthesia-related cooperation in this vulnerable population. The …

3 - 18 years of age All Phase N/A
T Tomasz Skladzien, phd md

Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA

Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols. Replacing opioids with non-opioid analgesics, co-analgesics, and regional and local anesthesia techniques allows avoiding the adverse effects of opioids while maintaining satisfactory analgesia. This is of particular importance in bariatric surgery, where reducing …

18 - 75 years of age All Phase N/A
S Sung Gwe Ahn, MD, PhD

A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia

In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain. The enrolled patients will be randomly assigned into two groups with 1:1 ratio. Chronic pain will be evaluated at 1 year after mastectomy based on the Breast Cancer Pain …

19 - 80 years of age Female Phase 3
y yupei chen, bachelor

The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy

In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications and does not increase the incidences of delirium and postoperative nausea and vomiting.

18 years of age All Phase N/A
y yuan Bi, Dr.

ED90 of Remimazolam Anesthesia Induction in Drug-induced Sleep Endoscopy in Adults

Exploring the ED90 of remimazolam in Drug-induced Sleep Endoscopy in adults at different BMI groups.

18 - 65 years of age All Phase 4
A Amani BEN HAJ YOUSSEF

Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia

A prospective, bicentric, randomized, double-blind controlled study including parturients scheduled for elective caesarean delivery under spinal anaesthesia and randomized and assigned to one of the two groups: Group O ondansetron : receiving Intravenous (IV) ondansetron 0.10 mg/ kg diluted in 5 ml normal saline, 5 min before spinal anesthesia Group …

18 - 45 years of age Female Phase N/A
A Ahmed M Shaat, MD

Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries

Objectives: To compare the safety and efficacy of oral atenolol versus oral metoprolol as a premedication for controlled hypotensive anesthesia during nasal surgeries. Background: Mucosal bleeding is the most frequent complication with nasal surgeries, as it interferes with the optimal visualization of the intranasal anatomy, increases operation time, and consequently …

21 - 50 years of age All Phase 4

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