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acute-pain Clinical Trials

A listing of acute-pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 358 clinical trials
P Pavanpreet Kaur, Resident

Pain After Buffered Vs Non Buffered Articaine

Pain after buffered versus non buffered articaine.

18 - 60 years of age All Phase 2
N Natalia Alexeeva, PhD

Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

Multi-center, randomized, blinded, sham-controlled study to determin the safety and efficacy of the NOVABLOC system on post-operative pain in patients undergoing TKA procedures.

21 years of age All Phase 2/3

ShotBlocker, Cold Needling, and Both Methods in Combination Pain and Satisfaction

Intramuscular (IM) injections are one of the most frequently used pharmacological treatment methods in nursing practice. Reducing the pain experienced by patients during this procedure and ensuring patient satisfaction are important indicators of treatment quality. Reducing injection-related pain should be a priority in nursing care for both patient safety and …

18 - 65 years of age All Phase N/A

Sensory Distribution and Postoperative Analgesia of Ultrasound-Guided Interfascial Plane Blocks in Living Liver Donors

Living liver donor hepatectomy at our institution routinely includes ultrasound-guided interfascial plane blocks as part of postoperative analgesia. Although these blocks have become increasingly used in donor hepatectomy, their cutaneous sensory distributions and block-related dermatomal coverage have not been systematically evaluated, with only anecdotal reports available in the literature. This …

18 - 65 years of age All Phase N/A

A Study of Single and Multiple Doses of HRS-6257 in Healthy Subjects

This is a phase I, randomised, single-blind placebo-controlled, 2-part study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of single and multiple oral doses of HRS-6257 in healthy volunteers.

18 - 55 years of age All Phase 1
J Jada Malveaux, MA

Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain

The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)

18 - 60 years of age All Phase N/A

A Handheld Tool for Active Distraction of Children and Adolescents During Painful Procedures

The goal of this clinical trial is to learn if the handheld device Grasp, works to reduce pain and distress during small procedures involving a needle prick in children and adolescents. The main question it aims to answer is: Does repetitive squeezing of the Grasp device during the painful procedure …

8 - 15 years of age All Phase N/A
S Syed Saad Aftab Mohiuddin, BDS

COMPARISION OF CONVENTIONAL BUCCAL NERVE BLOCK VERSUS BUCCAL NERVE TRUNK BLOCK DURING EXTRACTION OF POSTERIOR MANDIBULAR TEETH

This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular molars.

20 - 60 years of age All Phase N/A
A Amélie Desaulniers

Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial

The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain. Researchers will compare this treatment to a placebo, compresses soaked in water. Participants will be invited to use their compresses if …

18 years of age Female Phase 2
R Rachel Henning

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants. Deep Inferior Epigastric Perforator (DIEP) flaps are the gold standard for autologous breast reconstruction . Effective pain control following surgery …

18 - 70 years of age Female Phase N/A

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