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low-blood-pressure-hypotension Clinical Trials

A listing of low-blood-pressure-hypotension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 122 clinical trials
Y Yasin Tire, MD

The Noninvasive Blood Pressure Measurement Effect on the Hypotension

Around 300 million surgical operations are performed globally, and of these, 40 to 50 million are performed in the USA. The perioperative period is characterized by hemodynamic instability and, most importantly, hypotension. Intraoperative hypotension is frequent, and the incidence ranges between 5% and 99% during non-cardiac surgery, depending on the …

18 - 100 years of age Both Phase N/A
Y Yi Chen, M.D.

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension

The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on neonatal outcomes following cesarean section.

18 - 45 years of age Female Phase N/A
B Benjamin Friedman, MD

Duloxetine for LBP

This research study will help determine whether a medication called duloxetine can improve back pain. It is well documented that many participants who come to the ER with acute low back pain still have low back pain 3 months later. The investigator team will attempt to determine whether duloxetine can …

18 - 64 years of age Both Phase 4

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor

Currently, there is no medication available to adequately treat patients undergoing hemodialysis who are suffering from intradialytic hypotension (IDH). Medical interventions such as Trendelenburg positioning, saline bolus administration, reduction of ultrafiltration rate, interruption of the hemodialysis, and other medical treatments are the methods of choice to treat the hypotensive condition …

18 - 80 years of age Both Phase 3
D Dewinter, PhD

Hypotension Prediction Index for Shoulder Surgery in Beach Chair.

The beach chair position is the most commonly used position during shoulder surgery and offers the surgeon numerous advantages over the lateral decubitus position. However, the beach chair position can also lead to hemodynamic changes, including hypotension and cerebral hypoperfusion. It is therefore the anesthesiologist's job to prevent hypotension during …

18 - 85 years of age Both Phase N/A
J Jorge L Gamboa, M.D. Ph.D.

Hemodialysis.-Induced Hypotension Therapy for End Stage Kidney Disease

Bradykinin is a potent vasodilator that is formed by the activation of the kallikrein-kinin system. We and others have shown that bradykinin increased during hemodialysis; however, the role of bradykinin in dialysis-induced hypotension (DIH) has not been evaluated. Preliminary results from a pilot clinical trial showed that bradykinin B2 receptor …

18 - 85 years of age Both Phase 2
O Olivier Hanon, MD PhD

Efficacy and Tolerance of Flucortac in Patients With Orthostatic Neurogenic Hypotension

To evaluate the efficacy of a 4-week fludrocortisone (FLU) treatment on systolic blood pressure depression after 5 minutes of active orthostatism in patients with neurogenic orthostatic hypotension (HON) symptomatic, despite treatment with non-drug measures with or without midodrine.

18 - 100 years of age Both Phase 4

Hypotension Prediction With HPI Algorithm During Decessed-donor Kidney Transplant (HPI2022)

HPI monitoring and the adoption of therapeutic interventions before hypotension occurs should be ensure a shorter time of intra-operative hypotension (MAP < 65 mmHg) during deceased-donor kidney transplant surgery. The control group is represented by patients undergoing the same surgical procedure with hemodynamic monitoring with invasive blood pressure monitoring which …

18 - 100 years of age Both Phase N/A
C Christelle NGUYEN, MD, PhD

Efficacy of a Short Multidisciplinary Education and Rehabilitation Program for Patients With Subacute and Chronic Low Back Pain (LBP) (LOMBAFAST)

The main purpose of this study is to assess the clinical efficiency of an intervention including a short multidisciplinary program of education and rehabilitation and a personalized follow-up, in patients with subacute and chronic low back pain and no severe disability. The secondary objectives are: to assess the capacity of …

18 - 100 years of age Both Phase N/A

Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium

Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and mitigate potential complications. Preserving blood flow, especially to the brain, heart, and kidneys, is vital during this method. Previous studies on the …

18 - 65 years of age Both Phase N/A

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