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renal-failure Clinical Trials

A listing of renal-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 614 clinical trials
W Wang Meixia

A Pharmacokinetics and Safety Study of Azvudine Tablets in Subjects With Mild-To-Moderate GFR Decline in Renal Insufficiency and in Healthy Subjects

Azvudine(FNC),a nucleoside reverse transcriptase inhibitor, make itself a better candidate to be co-formulated in other anti-HIV therapies, thus to improve patient's compliance. FNC is a broad-spectrum RNA virus inhibitor that inhibits the novel coronavirus RNA-dependent RNA polymerase. This trial uses a non-randomized, open-label, parallel, single-dose adaptive design aimed at investigating …

18 - 70 years of age All Phase 1

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

The purpose of this study is to help determine the right dose of LY3537982 in participants with kidney problems, particularly those with severe kidney problems. The study will last about 43 days for each participant.

18 - 85 years of age All Phase 1
P Per Skoog, MD, PhD

Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm

This randomized controlled trial aim to determine the impact on renal function after treatment for infrarenal abdominal aortic aneurysm (AAA) with stentgrafts either with active supra- or infrarenal fixation.

18 - 90 years of age All Phase N/A
S Serafim Guimarães, MD

Pharmacokinetics and Safety of Rupatadine in Participants With Renal Impairment Compared to Control Participants

The purpose of this study is to assess the PK, tolerability, and safety of rupatadine (10 mg) and its active metabolites in participants with renal impairment compared to matched control participants with normal renal function. The study duration will be up to 40 days, including Screening, Baseline, Study Period, and …

18 years of age All Phase 1
S Simon Abelson, Medical Director

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

This a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.

18 - 75 years of age All Phase 1

Effect of Renal Impairment on Enpatoran Pharmacokinetics

The purpose of this study is to assess the effect of renal impairment on the pharmacokinetics of enpatoran.

18 - 80 years of age All Phase 1

Pharmacokinetics of Petrelintide Following Administration to Participants With Impaired Renal Function

This clinical research study is testing the study compound petrelintide that is being developed for the weight management in people with obesity or overweight with comorbidities or related diseases. The aim of this clinical research study is to investigate whether the effects of petrelintide will be different in people with …

18 - 65 years of age All Phase 1

Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls

The purpose of this study is to assess the pharmacokinetics (PK), safety, and tolerability of BPN14770 in participants with severe renal impairment and those with normal renal function.

18 - 85 years of age All Phase 1

A Phase I Study to Investigate the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

This study is being conducted to investigate the PK, safety, and tolerability of opemalirsen in participants with renal impairment, compared to participants with normal renal function.

18 - 80 years of age All Phase 1

A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls

The purpose of this study is to measure the pharmacokinetics, safety, and tolerability of S-892216 (S-892216-PO) in participants with mild, moderate, or severe renal impairment not on dialysis, or renal impairment requiring hemodialysis (HD), and in participants with normal renal function.

18 - 80 years of age All Phase 1

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