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renal-failure Clinical Trials

A listing of renal-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 609 clinical trials

Evolution of Bone Histomorphometry and Vascular Calcification Before and After Renal Transplantation

A study of the natural history of bone and mineral disease (BMD) in patients with end-stage renal disease before and after kidney transplantation

18 years of age All Phase N/A
N Naciye Vardar-Yağlı, Prof. Dr.

Functional Capacity in Children with Chronic Kidney Disease

The aim of our study is to assess the functional capacity of children with chronic kidney disease using various tests.

6 - 18 years of age All Phase N/A
P Pei Nie

Multimodal Imaging Assessment of Chronic Kidney Disease Patients at Different Stages From a Cardio-Renal Interaction Perspective

This study is a prospective cohort investigation in which consecutive eligible patients undergo 18F-FAPI PET/MR imaging. Chronic kidney disease (CKD) participants are stratified into two groups:Group I :CKD stages 1-3(eGFR ≥ 30 mL/min/1.73 m²),Group II :CKD stages 4-5(eGFR < 30 mL/min/1.73 m²). Using 18F-FAPI PET/MR, we will evaluate global cardiac …

18 - 80 years of age All Phase N/A

Intestinal Transport of Microbial Metabolites in Chronic Kidney Disease

Chronic kidney disease is associated with the accumulation of various metabolites, i.e., uremic retention solutes. Evidence is mounting that the colonic microbiome contributes substantially to these uremic retention solutes. Indoxyl sulfate and p-cresyl sulfate are among the most extensively studied gut microbial metabolites, and are associated with cardiovascular disease, chronic …

18 - 85 years of age All Phase N/A
O Oliver Gross, MD

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

The hereditary type IV collagen disease Alport syndrome inevitably leads to end-stage renal disease. Currently there are no therapies known to improve outcome. Our non-interventional, observational study investigates, if medications such as ACE-inhibitors can (1) delay time to dialysis and (2) improve life-expectancy within three generations of Alport-families in Europe.

years of age All Phase N/A
V Valerie St-Pierre, M.Sc

Acetoacetate and Acetate Metabolism in Patients With Chronic Kidney Failure.(RENO-TEP)

The objective of this study is to nake a comparison between 11c-acetate and 11c-acetoacetate kidney uptake in chronic kidney failure patients.

18 years of age All Phase N/A
Z Zheng Jie, Associate professor

The Influence of Internet + Combined Family Empowerment Management Mode on Treatment Compliance of PATIENTS With CKD

To explore the effect of Internet + combined family empowerment management mode on treatment compliance of patients with chronic kidney disease (CKD) and the correlation between psychological status and disease progression.

40 - 60 years of age All Phase N/A
D Danit Silberman

AK+ Guard™ Pilot Study in Chronic Kidney Disease: Outpatient Diagnostic Accuracy and Remote Monitoring

The goal of this observational pilot study is to evaluate the investigational AK+ Guard™ software as a medical device (SaMD) for detection of moderate to severe hyperkalemia (serum potassium (K+) ≥ 6.5 mmol/L) in adults with chronic kidney disease (CKD). Study objectives are: Arm 2A (Outpatient Diagnostic Accuracy): To generate …

22 years of age All Phase N/A
M Marcello Demetri, Biology

Comparison of Hemodialysis Techniques in the Removal of Uremic Toxins in Chronic Renal Failure

In recent years, expanded hemodialysis has been the subject of studies, many of them done on small populations, with limited observation periods and not always unambiguous results. In the literature, there are data comparing HDx and high-flow hemodialysis in terms of small- and medium-molecule purification and control of inflammation indices; …

18 years of age All Phase N/A

TESTING -ON Post-Trial ObservatioNal Cohort Study

The primary aim of this study is to extend follow up of TESTING study participants and to assess the long-term effects of a 6-9-month course of oral methylprednisolone on End Stage Kidney Disease (ESKD), according to dose (full-dose vs reduced-dose), ethnicity (Chinese vs other) and kidney function (eGFR above and …

18 - 100 years of age All Phase N/A

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