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renal-failure Clinical Trials

A listing of renal-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 606 clinical trials
k kun-Ling Tsai, Ph.D.

The Effects of Eccentric Cycling Exercise Program in Chronic Kidney Disease Patients

Progress in medical technology, enhancements in environmental cleanliness, and elevated living conditions have notably prolonged the mean life expectancy, resulting in a swift increase in the aging population. The prevalence of Chronic Kidney Disease (CKD) is more pronounced among the elderly in contrast to younger demographics. With the aging of …

55 - 85 years of age All Phase N/A

Impact of Dapagliflozin in Anemic Chronic Kidney Disease Patients

Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, primarily used in the management of type 2 diabetes mellitus. Emerging research suggests that SGLT2 inhibitors may offer additional benefits, including reducing the risk of cardiovascular events and renal complications. Post hoc analyses of previous clinical trials have shown that patients treated …

18 years of age All Phase 2
Z Zhe Li

Calcium-Phosphorus Regulation Therapy on Heart Valve Disease

The goal of this clinical trial is to learn if calcium-phosphorus regulation therapy can slow the progression of heart valve calcification in patients with degenerative heart valve disease and chronic kidney disease (CKD). The main questions it aims to answer are: Does Sevelamer lower the progression of heart valve calcification …

50 years of age All Phase 4
R Rhianna Patel

Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose …

55 years of age All Phase N/A
A Arline Mata

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

The purpose of this first-in-human (FIH) study is to evaluate safety, tolerability, pharmacokinetic (PK) of OJR520.

18 - 65 years of age All Phase 1
Z Zhao Minghui

UBT251 Injection Phase II Clinical Study (CKD)

This multicenter, randomized, double-blind, placebo-controlled phase II clinical study to evaluate the efficacy and safety of UBT251 injection in obese/overweight chronic kidney disease (CKD) population

18 - 75 years of age All Phase 2
k kun-Ling Tsai, Ph.D.

Exploring the Effects of Exercise Combined With BFRT on Healthy and Patients With CKD

Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in healthy and CKD patients

20 - 85 years of age All Phase N/A

Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population

The purpose of this pilot interventional study is to collect preliminary data on the application of a transcutaneous auricular vagal nerve stimulation (taVNS) device in patients with chronic kidney disease (CKD). This data will enhance understanding of the short-term safety, tolerability and effects of this novel therapeutic approach in the …

18 - 80 years of age All Phase N/A
G Gemma Beltran, MPH

Safety of Short-course of NSAIDs in Pediatric Patients With CKD

The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney disease (CKD). The investigators hypothesize that there is no increased risk. This will be a limited pilot study …

18 years of age All Phase 4
P Peter C Rossing, MD,PHD, PROF

A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic Kidney Disease

Over 800 million people worldwide suffer from chronic kidney disease (CKD), which is associated with a high individual disease burden for those affected, multiple secondary diseases, frequent doctor contacts, and hospitalizations, but also outstanding costs for the health system and the solidarity community. Appropriate interventions are essential to prevent the …

18 - 75 years of age All Phase 4

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