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idiopathic-thrombocytopenic-purpura-itp Clinical Trials

A listing of idiopathic-thrombocytopenic-purpura-itp medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 18 clinical trials

Study of PN20 in Adult Patients with Primary Immune Thrombocytopenia (ITP)

The main aim of this clinical trial is to assess the safety and tolerability of PN20 in adult patients with primary immune thrombocytopenia (ITP). The main questions it aims to answer are: Is PN20 safe in these patients? Could these patients potentially benefit from PN20 treatment? Participants will Receive one …

18 - 65 years of age All Phase 1
T Ting Sun, M.D

TPO-RAs Combining Anti-CD 20 Monoclonal Antibody Versus TPO-RAs in the Management of Pediatric Primary Immune Thrombocytopenia (ITP)

This multicenter randomized, open-label study aim to compare the efficacy and safety of TPO-RAs combining anti-CD 20 monoclonal antibody with TPO-RAs in China pediatric ITP patients .This study will be conducted in persistent or chronic pediatric ITP patients who had not responded to or had relapsed after previous glucocorticoid treatment.

6 - 17 years of age All Phase 4
Y Yi Fang, MD

A Phase Ib/II Clinical Trial of Multiple Doses of STSA-1301 Subcutaneous Injection in Healthy Subjects and Patients With Immune Thrombocytopenia (ITP)

A randomized, double-blind, placebo-controlled design was designed to evaluate the safety and tolerability, pharmacokinetic/pharmacodynamic profile, and immunogenicity of multiple administration of STSA-1301 subcutaneous injection in healthy subjects and patients with ITP, and to further explore the initial efficacy of STSA-1301 subcutaneous injection in patients with ITP

18 - 75 years of age All Phase 1/2
S Shuo Chen, MD

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

This exploratory study is to investigate the efficacy, safety and tolerability of Lusutrombopag in the treatment of primary immune thrombocytopenia in Chinese patients who have failed first-line therapy

18 years of age All Phase 2
T Ting Sun, M.D

Anti-CD38 Antibody Treating Pediatric Primary Immune Thrombocytopenia (ITP)

To evaluate the safety and efficacy of Anti-CD38 Antibody in the treatment of pediatric primary immune thrombocytopenia in patients who have not responded adequately or relapsed after first-line treatment and at least one second-line therapy including Anti-CD20 Antibody and/or TPO-RA, or those in whom no other second-line treatment options are …

6 - 17 years of age All Phase 2
T Ting Sun, M.D

Anti-CD38 Antibody Treating Children With Primary Immune Thrombocytopenia (ITP)

To evaluate the safety and efficacy of Anti-CD38 Antibody in the treatment of primary immune thrombocytopenia in patients who have failed first-line treatment.

6 - 18 years of age All Phase 2
T Ting Sun, M.D

Anti-CD38 Antibody Treating Elderly Patients With Primary Immune Thrombocytopenia (ITP)

To evaluate the safety and efficacy of Anti-CD38 Antibody in the treatment of elderly patients with primary immune thrombocytopenia in patients who have failed multiple treatment.

60 years of age All Phase 2
J Jinhui Shu

Safety and Efficacy of PRG-1801 in Recurrent/Refractory Immune Thrombocytopenia (ITP)

This is a single center, open-label, 3+3 dose escalation, early phase 1 study to evaluate the safety, tolerability, and preliminary efficacy of PRG-1801 for patients with relapsed/refractory immune thrombocytopenia (ITP).

18 years of age All Phase N/A
S Shuo Chen, MD

TPO-RA in Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 Years

This multi-center study aims to study the efficacy of TPO-RAs' transformation in Chinese ITP patients older than 14 years. This study will be conducted in ITP patients who had not responded to first-line in the previous treatment .

14 years of age All Phase N/A

A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP)

The main objective is to assess the safety and tolerability of budoprutug in adults with ITP. Pharmacokinetics, pharmacodynamics, and preliminary clinical efficacy will also be assessed.

18 years of age All Phase 1/2

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