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infantile-spasms Clinical Trials

A listing of infantile-spasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 15 clinical trials
A Abdulwasiu Bolaji Tiamiyu

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults and Children Residing in West Africa

18 - 70 years of age Both Phase 2
K Kullasate Sakpichaisakul, MD

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm

Infantile spasms (IS) are seizures associated with a severe infantile epileptic encephalopathy. Both cessation of spasms and electrographic response are necessary for the best neurodevelopmental outcomes. Adrenocorticotrophic hormone (ACTH), or prednisolone, or vigabatrin are considered the first-line treatment individually. However, ACTH expense and availability are the barriers in developing countries …

2 - 14 years of age Both Phase N/A
C Charlotte Lynskey, SRC

Treatment of Refractory Infantile Spasms With Fenfluramine

This is a phase II clinical trial in which children with refractory infantile spasms (also called epileptic spasms or West syndrome) will be treated with fenfluramine, to evaluate efficacy, safety, and tolerability. Patients with infantile spasms that have not responded to treatment with vigabatrin and ACTH we will be invited …

12 - 36 years of age Both Phase 2
S Suvasini Sharma, DM

Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study

This study has been planned to compare the efficacy and tolerability of topiramate, a commonly used second line agent, with modified Atkins diet in children with epileptic spasms refractory to hormonal treatment, in a randomized open label study.

9 - 3 years of age Both Phase 2/3
M Mme Anne-Charlotte TAUVERON

Evaluation of the Impact of Therapeutic Education Workshops for COPD Patients in the North-West Val d'Oise Area

The aim of this study is to assess the impact of the Patient Therapeutic Education (PTE) workshops offered by the Maison de Prévention de la Santé et d'Accompagnement Thérapeutique (MPSAT) on the follow-up and feelings of the COPD patients who take part. These workshops are organised outside the hospital environment …

18 - 100 years of age Both Phase N/A
G Gregory N Kawchuk, PhD

Alberta Back Care Pathway (ABCp) - Edmonton West Primary Care Network (EWPCN) & Alberta Health Services' Calgary Chronic Pain Centre (CPC)

Every year, the pain, disability, addiction, and expense associated with LBP increase in Alberta. This escalation is largely because most people with LBP seek care from family physicians who are unable to provide effective, guideline-based interventions due to three recognized barriers: 1) a lack of training, 2) a lack of …

18 - 100 years of age Both Phase 2

Characterization by Automated System on Infantile Spasmes

Infantile spasms are defined by the occurrence of epileptic episodes characterized by the appearance of very specific motor seizures, made up of rapid, repeated contractions in flexion or extension known as spasms. This syndrome is of high concern as it will lead to mental retardation if it is not early …

- 3 years of age Both Phase N/A
B Beth Sheidley, MS,CGC

Genetics of Epilepsy and Related Disorders

Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to epilepsy and related disorders. These findings may help explain the broad spectrum of clinical characteristics and outcomes seen in people with epilepsy.

- 100 years of age Both Phase N/A
S Sandra BERNARD, PM

Follow-up of Patients With Multiple Myeloma in the West-Occitanie Region "Living With a Myeloma in West-Occitanie"

Actually very few real life data are available for patients with multiple myeloma (MM), whereas they're playing a more and more important role in health care decisions. Treatments choice for medical care of patient with MM depends of their age, their general status, their eligibility to high dose treatment (autograft), …

18 - 100 years of age Both Phase N/A
C Clement Adebamowo, M.D.

Genetics of Type 2 Diabetes in West Africans

Background Type 2 diabetes (T2D) and associated complications are major contributors to the global disease burden. T2D is already a major health threat in populations in developed countries and is rapidly taking hold in the developing world. It is believed that understanding the complex interplay between genetic and lifestyle characteristics …

18 - 120 years of age Both Phase N/A

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