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hyponatremia Clinical Trials

A listing of hyponatremia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 15 clinical trials
B Benjamin ZUBER, PH

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia

ICU patients with severe hyponatremia and a high risk of rapid SNa overcorrection.

18 - 100 years of age Both Phase 3
V Volker Burst, MD

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges

Hyponatremia is the most common electrolyte disorder of all and can be observed in more than 30% of all patients in hospitals. Osmotic homeostasis of body fluids is essential for survival of all living creatures. It is widely accepted that extra- and intracellular osmolalities are in equilibrium at all times …

18 - 100 years of age Both Phase N/A
E Elizabeth McCracken, MS, CGC

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

This is a medical research study to test a medication in patients 4 years of age and older with a disease called medium-chain acyl-CoA dehydrogenase deficiency (MCADD) caused by the common ACADM c.985 A>G (K304E) mutation. The medication is sodium phenylbutyrate (ACER-001), which is currently FDA approved for the treatment …

4 - 100 years of age Both Phase 2
M Mirjam Christ-Crain, Prof.

Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis

The goal of this study is to assess the impact of protein supplementation on hyponatremia caused by the syndrome of inappropriate antidiuresis during hospitalization.

18 - 100 years of age Both Phase N/A
S Stefan Fischli, MD

Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia

Hyponatremia is the most common electrolyte derangement occurring in hospitalized patients. It is usually classified as hypovolemic, euvolemic or hypervolemic. The most common aetiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Hypervolemic hyponatremia is common in patients with congestive heart failure (CHF) (10-27%) and liver cirrhosis (up …

18 - 100 years of age Both Phase 4
M Mirjam Christ-Crain, Prof.

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

This study is looking at two new parameters, aSID and ChU, to see if these can help physicians to distinguish between different causes of low sodium levels (hyponatremia) in Patients taking a medicament against high blood pressure (thiazide). Researchers also want to see if using these new parameters to decide …

18 - 100 years of age Both Phase N/A
S Sabahattin Anil Ari, Asst. Prof.

Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy

Minimally invasive applications are seen as the gold standard in today's gynecology practice and are frequently preferred by both patients and physicians. Less pain, shorter hospital stays, and better cosmetic results brought about by minimally invasive applications further increase their preference. One of these approaches is hysteroscopic interventions. Although hysteroscopy …

18 - 65 years of age Female Phase N/A
V Volker Burst, MD

Analysis of the Epidemiology, Clinical Presentation and Therapy as Well as Therapy-associated Risk of Demyelination Syndrome in Patients With Profound Hyponatremia in the Emergency Department

Hyponatremia is a frequent cause for presentation to the emergency department (ED). While patients with chronic hyponatremia often exhibit minor symptoms, acute development of hyponatremia can lead to global cerebral edema, transtentorial herniation and death. The time course of hyponatremia development is usually not known to the treating physician at …

18 - 100 years of age Both Phase N/A
T Thomas RITZENTHALER, MD

Interest of Impedancemetry in Monitoring Hydration and Hyponatremia During Subarachnoid Hemorrhages

Subarachnoid hemorrhage (SAH) is a rare and serious form of stroke, mainly linked to the rupture of an intracranial aneurysm responsible for bleeding into the meningeal spaces. The main late serious complication is delayed cerebral ischemia (DCI), resulting in the appearance of new neurological deficits. Prevention of ICR involves in …

18 - 100 years of age Both Phase N/A

Samsca Post-marketing General Drug Use-results Survey in Patients with Hyponatremia in SIADH

The purpose of this study is to confirm the safety of tolvaptan in patients with hyponatremia in syndrome of inappropriate antidiuretic hormone secretion (SIADH) in Japan

- 100 years of age Both Phase N/A

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