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High Blood Pressure Clinical Trials

A listing of High Blood Pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 848 clinical trials

Fasciotens to Treat an Open Abdomen - a Prospective Cohort Study

The open abdomen can occur as a result of various diseases. After infections of the abdomen, compartment syndromes or traumata, it is essential for survival (1). This condition of the open abdomen lasts from days to months. Within a very short time, the fascia and abdominal wall structures retract in …

18 years of age All Phase N/A
D Dou-Sheng Bai, MD

The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients

In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.

18 years of age All Phase N/A
M Mingyuan Zhao

Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis

Background Handgrip strength , a core indicator of muscle function, has been confirmed to be significantly associated with the clinical prognosis of patients with liver cirrhosis. However, no studies have explored its correlation with portal venous hemodynamics. Objective The purpose of the study is to examine the effects of Handgrip …

18 years of age All Phase N/A

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Subcutaneous Injection of HRS-9563 in Subjects With Mild Hypertension: a Randomized, Double-blind, Placebo-controlled Phase I Study.

To evaluate the safety and tolerability of a single subcutaneous injection of HRS-9563 in hypertensive subjects

18 - 65 years of age All Phase 1
V Vittorio Porciatti, MD/PhD

CLAD Deconvolved PERG Responses in Glaucoma Patients

Glaucoma is a progressive disease resulting in blindness. Determining the onset of the disease is critical so patients may obtain treatment to preserve useful vision. This study will collect data from a population of glaucoma suspects (with positive factors for the disease but with normal vision) along with a population …

18 - 85 years of age All Phase N/A
J Jenifer Fahey, CNM, PhD

Enhancing Care & Outcomes for Patients During the First Postpartum Year

The United States is in the midst of a maternal mortality and morbidity crisis, with more than half of maternal deaths occurring within the first postpartum year. Patients with hypertensive disorders of pregnancy (HDP) and diabetes have been found to be particularly high-risk, as they have a significantly increased risk …

18 years of age Female Phase N/A
K Kimberlee Weaver-Lewis, RN

A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)

Congenital diaphragmatic hernia (CDH) occurs in approximately 1 in 3000 US live births, similar to the incidence seen within the Utah Birth Defects cohort. The diaphragmatic defect compromises lung growth and alters pulmonary vascular development. This is reflected postnatally as respiratory failure, pulmonary hypertension (PH) and overall cardiopulmonary dysfunction, particularly …

years of age All Phase 2
D Dominik Bettinger, PD Dr.

Early TIPS in Patients With Liver Cirrhosis and Ascites

The aim of this clinical trial is to compare the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) implantation with standard treatment (diuretic medications, and if necessary, paracenteses) in patients with liver cirrhosis and development of ascites as the first decompensating event. By creating a shunt between the liver …

18 - 80 years of age All Phase N/A

Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women

The purpose of this study is to conduct a pilot randomized controlled trial of a food is medicine community health worker intervention called the Women's Health Delaware Food Farmacy compared to the usual standard of care among pregnant ChristianaCare patients at risk for adverse clinical outcomes. The pilot study has …

18 years of age Female Phase N/A
L Lena M Haiden, MD

Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery

The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.

18 years of age All Phase N/A

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