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High Blood Pressure Clinical Trials

A listing of High Blood Pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 848 clinical trials
Y Yolanda Cartwright, PhD, RD

Church-based Intervention to Improve Blood Pressure in African Americans

This is a 12-month behavioral cluster-randomized trial testing a church-based intervention to reduce blood pressure in African Americans with uncontrolled blood pressure.

18 years of age All Phase N/A
A Austin T Robinson, PhD

Ketone Ester and Acute Salt (KEAS) in Young Adults

Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs the ability of systemic blood vessels and the kidneys to control blood pressure, which contributes to excess salt consumption being associated with increased risk for …

18 - 39 years of age All Phase N/A
D Delphine LAZARO

Sexual Dysfunction in Hypertensive Women

Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia. Hypertension is a contributing factor, and nonadherence to medication could amplify it. There are several ways to assess …

18 years of age Female Phase N/A
S Sabine de Bruijn

Controlling and Lowering Blood Pressure With the MobiusHD™

To perform post-market surveillance and evaluate the performance of the MobiusHD System in subjects with primary resistant hypertension.

18 - 80 years of age All Phase N/A
G Grégoire Wuerzner, MD

Multicentric Prospective Clinical Study to Evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) Device Compared to Standard Home Blood Pressure Monitoring (HBPM) in Hypertensive Patients When Blood Pressure Lowering Medications Intake

Prospective, multicentric, randomised, comparative study Study duration: 13 weeks in total Population: 30 hypertensive (Stage 1 or 2) participants (25 participants minimum) Device Under Test (DUT): Aktiia device Reference: HBPM (Aktiia cuff) Periods of treatment: 2 weeks of treatment for each drug followed by a washout period of 2 weeks …

21 - 85 years of age All Phase N/A

FlashPoint Renal Denervation Under Columbus 3D Mapping System Guidance for Treating Hypertension

To verify the safety and effectiveness of the renal artery radiofrequency ablation system under the guidance of the three-dimensional cardiac electrophysiological mapping system in the renal denervation of essential hypertension.

18 - 70 years of age All Phase N/A
S Steven A Romero, PhD

Targeting Endoplasmic Reticulum Stress in Human Hypertension

There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill this gap by performing a single-blind, placebo-controlled trial in humans with hypertension.

18 - 80 years of age All Phase 1/2
J Job van Steenkiste, MD, MsC

Telemonitoring and E-Coaching in Hypertension

Rationale: Hypertension is the most significant risk factor for cardiovascular disease and can be mitigated by lifestyle and medical management. Telemonitoring as a novel management approach to perform hypertension management at distance has been thriving but became indispensable during the COVID-19 pandemic. However, evidence of an effective implementation for telemonitoring …

18 years of age All Phase N/A
X Xin Zheng, MD,PhD

Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

In this multicenter, randomized, placebo-controlled trial in pre-heat failure patients with hypertension and without diabetes, we will enroll 120 eligible patients to randomized to receive placebo or engagliflozin (10mg/d) for follow them for 6 months. The primary endpoint is the left atrial volume index, which reflects left ventricular diastolic function. …

40 - 75 years of age All Phase 4
J John Ko, M.Sc

Stretching vs Walking for Lowering Blood Pressure

High blood pressure is a leading risk factor for cardiovascular disease. Traditionally, one of the ways to treat or prevent high blood pressure is to prescribe aerobic exercise training (i.e. brisk walking). Stretching may also be effective because it may cause changes in blood vessel stiffness and therefore reduce resistance …

18 years of age All Phase N/A

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